Intra-thecal Administration (Lumbar Puncture)

Stem cell information

Intrathecal administration is the infusion of stem cells via injection into the spinal canal, most popularly known as lumbar puncture. By using this route of administration blood brain barriers are avoided ensuring maximum delivery of cells into the cerebrospinal fluid. This route is particularly efficient in neurological disorders.

For the infusion of cells, puncture is made in the lumbar region; which is the lowest vertebrate at the back from where some spinal fluid is extracted. The administrator will ensure that the volume of the spinal fluid extracted will be equivalent to the amount of stem cells infused.

This will ensure that there is very little pressure difference in the spinal fluid space.

Any change in pressure of the fluids in the spinal cord may cause a little headache and dizziness in the patient. This symptom is not very hazardous and it lasts only for 1 or 2 days. However, many a times this pain can be uncomfortable especially while getting up from a horizontal position due to the change in the pressure ratios.

More detailed information on the LP procedure is available in the LP Informed Consent Document (PDF File).

Stem cells can be implanted in other following major ways depending on protocol. They are:

      arrow imageIntravenous Administration

      arrow imageIntramuscular Administration

      arrow imageIntra-arterial Administration via catheter

      arrow image Intravitreal Infusion

      arrow imageRetrobulbar Infusion of cells

      arrow imageLiberation Angioplasty for Multiple Sclerosis CCSVI

      arrow imageIntra-Dermal Administration

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