Erectile Dysfunctio



Erectile Dysfunction

Erectile dysfunction is mainly characterized by the inability to develop or maintain erection of the penis for a longer span, which can ultimately lead to Impotence. Although not life threatening by itself ED is a strong predictor of high mortality diseases such as coronary artery diseases, cardiovascular diseases.

An understanding of the basic physiology of erection will help us to fight efficiently against the disease. The erection mechanism is much like a firm tire, which is depending upon its hose for delivering an adequate amount of air in speedy fashion, and a valve mechanism that holds the air in place. In the penis the hose is represented by the erection arteries, which rapidly carry blood into the erectile bodies and the valve mechanism, while complicated in its structure, ensures that the blood is trapped inside the erectile bodies until ejaculation occurs or the sexual stimulus has passed.

Medical conditions listed above can block the erection arteries or cause scarring of erection bodies and prevent proper blood flow thus limiting the erection. While the majority of the ED patients is treated with currently available medications approximately 70% remain unresponsive to it. Apart from this all treatment options can treat only symptoms and not the underlying causes. But the research efforts for stem cell treatments have laid a foundation towards finding a long term solution that can reverse the pathogenesis of ED and thereby restore the patient's ability to achieve natural erection.


Major Manifestations of ED, in patients include the following:

  • Trouble getting an erection
  • Trouble keeping an erection
  • Reduced sexual desire

Conventionally, the treatment for ED involves the use of prostaglandin drugs, applicators, etc. However there long term use may welcome lot many other side effects such as visual abnormalities, hearing loss, dyspepsia, headache, coronary artery diseases etc. Moreover, the treatment appearing to be of temporary use and not a permanent solution.

In order to get a complete reversal of disease manifestation, stem cells can be the better option. These cells have proven their potential in a variety of clinical trials of male infertility.

Stem cells are the most naive cells of the body, which can differentiate into many new cells depending upon the requirement and the direction. They have evidently proven to promote angiogenesis, revascularization, improve blood flow, etc. Thus with the employment of Autologous stem cells from your own bone marrow and adipose tissue, it is now possible to find out a permanent symptomatic solution for the same.

The stem cell therapy approach mainly focuses on delivering the sufficient number of Adult Autologous Stem Cells which will travel into multiple areas of the damaged parts, remove blockages, promote blood flow.

Stem Cell Treatment

Stem Cell Treatment For ED: Advancells Protocol

Treatment at Advancells involves use of adult stem cells from patients very own body as a tool for repairing ED. We at Advancells are exploiting the most potent stem cells isolated from patients own Bone Marrow or Adipose Tissue or maybe both depending upon the assessment. Our top priority is to provide very comprehensive, individualized treatment pattern which is best suited for the patients undergoing treatment.

The patients suffering from erectile dysfunction are mainly treated by injecting the stem cells into the penile artery via catheter. Patients also have the option of getting the stem cell infused into the blood flow through the process of intravenous injection.

Step 1- Qualification For The Treatment

A safety and efficacy assessments will be prescribed by our experts in order to investigate the stage of severity and qualify the patient for the treatment. Following pretreatment assessments can be suggested depending upon the patient's medical and family background:

Pre-Treatment Assessments

  • Routine Blood Tests
  • Infectious Disease Testing
  • Urine Analysis
  • Physical Examination
  • Ultrasound
  • Overnight erection test

As per these results, the patient will be counselled further for final decision of protocol.

Step 2- Source Extraction

With the physician's approval and guidance, the source from which stem cells are to be collected is decided. In general patient can be prescribed, stem cells isolated from Bone Marrow or Adipose Tissue, as these are the most potent Autologous sources available. However, in certain cases, both sources can be utilized for a better outcome. Doctors can also suggest stem cell stimulation therapy for some, depending upon the severity and requirement.

The specified amount of samples will be extracted from the patient's own body on the intimated date and time, with the application of local anesthesia. The entire procedure takes around 7-8 hrs, however, in case of extracted from both the sources the patient has to be with us for a little longer time.

If you are curious to know more about the procedure, kindly refer our detailed snapshot below

stem cell treatment for ALS

Step 3- Laboratory Processing

The extracted sample, will be sent to the government approved cGMP laboratory for processing. The sample processing will be done in a state of the art class 10,000 clean room in compliance with the ISO and GMP standards.

The sample will undergo minimum manipulation in our complete automated Sepax technology to be enriched with the pure population of stem cell culture. The isolated stem cells will be characterized for quality, purity and viability.

The client will be given a third party certificate from Internationally Accredited Lab for the quality purpose.

Step 4- Stem Cell Implantation

Once stem cells are enriched and ready to be injected back into the body, we have worked on different modes of implanting them. However, depending upon the patient's physiological and mental well being, one of the following will be finalized by our experts.

Follow up Treatment

Post treatment, the patient will be asked to visit the doctors after a specific period of time, such as rehabilitation, ultrasound, counselling to understand medical problems, evaluation and follow up.



Erectile Dysfunction Stem Cell Treatment Results

The majority of the patients treated by us have shown marked improvement in muscle strength, endothelium and/or nerve in erectile tissue,improved social and intellectual behavioral pattern.



Frequently Asked Questions

  • Is Erectile Dysfunction a normal part of aging?
  • Erectile dysfunction doesn't have to be a part of getting older. Even older men can able to get an erection. On the contrary, 5-10% of the population has been reported to be below 35 years of age, who have been complaining about ED.
  • Is ED physical or psychological?
  • As firmer erection, has always been a combined action as a result of the whole series of psychological and physical events, it is associated with both the reasons.
  • Is it normal to get ED?
  • With the current reported data, many men suffer from this issue, however on a generalized note men with ED wait for 5 years before going to the doctor. Due to changes in their lifestyle pattern, eating habits and stress, it is observed to be more widely spread than a normal man could imagine. A person with ED, should not take the disease very lightly, as it may give rise to other complications such as diabetes.
  • What are the physical causes of ED?
  • The most common cause of ED is damaged to arteries, smooth muscles and fibrous tissues. The problems related to them can be caused by a variety of factors like diseases such as atherosclerosis, diabetes, multiple sclerosis, kidney diseases etc. Penile injuries may also lead to the major trouble. Additionally, complications with surgery or radiations can interfere with nerve impulses or blood flow to the penis. ED can also be the result of a side effect of common drugs taken for high blood pressure, antidepressants, tranquilizers, etc. Chronic use of alcohol, tobacco etc. can also cause ED aggravated by decreased sexual life.
  • What are the physiological problems associated with ED?
  • Psychological problems, such as anxiety or depression may interfere with the men erection process by distracting him from things that normally arouse him. These problems can be listed out as depression, relationship problems, anxiety, stress etc.
  • Does ED sometimes clear up by itself?
  • Yes, it does, especially if it was due to the result of stressful situation which has been resolved or an injury that has been healed.
  • Will I get embarrassed if I go to the doctor with this problem?
  • Medical practitioners can understand your problem, and can identify the root cause of it. He can also guide you to get over your mood swings or depression. It is always better to face the problem rather than hiding it. However, it is necessary to find the right person and right place with whom you can completely rely on.
  • How is it conventionally treated & diagnosed?
  • Conventionally, steroidal drug therapies, surgical methods were used to rectify the problem associated with the disability. However the long term use of these steroidal drugs can be very dangerous and can welcome some unknown side effects. However, these treatments proved to be very temporary with no reversal of damage and hence an alternative treatment was always in demands, that can reverse the damage associated with the disorder.
  • How can stem cells be beneficial to treat?
  • Undifferentiated adult autologous stem cells are mutable and can Metamorph into countless numbers of cells as per the requirement. This remarkable property of stem cells can be exploited for treating a variety of diseases. These cells can be isolated from the most potent sources of our own body known as Adipose Tissue and Bone Marrow. Upon implanting back into the body, these cells can rapidly multiply with greater speed to smooth obstructed blood flow, to promote networking of new blood vessels, to help control over your mood swings, etc. Additionally a stimulation therapy can also be applied, wherein the organ is stimulated to multiply resident stem cells and secrete growth factors to create microenvironment. This treatment will act as a booster to promote regeneration.
  • Why is stem cell treatment better than conventional treatment approach?
  • Conventional treatment approach highly invasive associated with many side effects. Although stem cells can naturally heal the body from damage and regenerate lost tissue specific cells to improve impaired functions. Additionally, since body's own cells are used for repairing, the entire treatment is minimally invasive without any side effects.
  • How do I know if I am the right candidate for the stem cell treatment?
  • There are many important issues to be addressed before opting for the treatment, which can satisfy answered only by experts. Thus, it is always advisable to consult, and opt for the right stem cell treatment pattern.
  • Where can I get more information about Disease?
  • Please go through, our treatment brochures for other ED related information.


What can you expect?

Many ED patients after stem cell treatment reported to be exhibiting:

  • Improved Muscle Strength
  • Improved social Behavior
  • Improved erection
  • Improved self regulation
  • Improved quality of life
  • Complete stoppage or progression of the disease

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