Degenerative joint disease, also known as degenerative arthritis or degenerative joint disease, are a group of mechanical abnormalities involving degradation of joints, including articular cartilage and subchondral bone. Symptoms may include joint pain, tenderness, stiffness, locking, and sometimes an effusion. When bone surfaces become less well protected by cartilage, bone may be exposed and damaged. As a consequence of decreased movement secondary to pain, regional muscles may atrophy, and ligaments may become more negligent.
With the potential to repair and regenerate new tissues and organs, stem cell therapy holds tremendous promise for the treatment of orthopaedic problems. In the 21st century, regenerative medicines using stem cell therapy has taken science to a new level giving options to treat incurable diseases.
Our (Advancells, India) clinical experiences and evidences allow us to adopt a twofold approach to joint injury with the use of stem cells and PRP (Platelet Plasma Therapy) to treat joint problems, to strengthen and regenerate the supporting structure of joints and further to heal permanently. The area of injury or arthritis is treated with both stem cells and platelet rich plasma (PRP). If stem cells are the seeds in the lawn, PRP is the fertilizer that helps the lawn grow. PRP, a compounding of growth factors and platelets naturally found in the body, provides cell signals and nourishment to help the stem cells flourish and develop into new joints, ligaments, tendons, and other body parts and heal permanently. PRP not only triggers stem cell growth, but can also help stem cells regenerate on their own in the body, and can also attract circulating stem cells in the region of injury. Thus, follow up treatments of PRP are given at monthly intervals to continue to allow the stem cells to do their work.
Degenerative arthritis is a progressive disorder of the joints caused by gradual loss of articular cartilage, which naturally possesses a limited regenerative capacity. The potential of intra-articular injection of stem cell in combination with PRP (A new and validated Treatment Regime) has been assessed in 30 patients with osteoarthritis. During a one-year follow-up period – comparison of magnetic resonance images (MRI) at baseline and six months post-stem cell injection displayed an increase in cartilage thickness, extension of the repair tissue over the subchondral bone and a considerable reduction in the size of oedematous subchondral patches in more than 80% of patients.
Many patients after stem cell treatment reported to be exhibiting:
The staff at the clinic was very friendly, efficient and overall I quite enjoyed the week Overall, I am very, very pleased with the result so far.
I feel much better than I was before. This morning, I attempted to run; something I have not been able to do for years. You are doing great work! Please keep me informed on any new progress.
I notice a huge improvement in both knees. I would recommend this type of treatment to anyone with knee, hip, elbow, shoulder pain or osteoarthritis.
To me stem cell therapy seemed like the best, last resort. Compared to the more invasive, time consuming, physically straining surgical options, stem cell therapy appears to be a minimally invasive, cost effective procedure that has brought me excellent results.
I really feel the quality of my life has improved since the treatment. I'm cautious with my ankles as I don't want to destroy the gains that I have made, so I'll only walk right now.