Rheumatoid Arthritis, commonly known to be as RA; is identified as an autoimmune as well as the inflammatory disorder, mainly affecting joints. The issue is mostly associated with joints of hands, wrists as well as knees and ankles, wherein the ligamental lining of joints is destroyed, due to self-inflammatory process, initiated by body’s own immune system. If not halted in its initial phases, the ailment can cause progressive, chronic tissue damage, unsteadiness and/or lack of balance as well as deformity. Moreover, in many cases, chronic condition is found to be affecting other vital organs of human body, like lungs, hearts, kidneys, etc.
Common Signs and Symptoms Associated with RA
The ailment is commonly associated with symptoms, which can variably flare up as well as subside; they may be generally noted as, pain in joints, joint stiffness, reddening or tenderness in joints, unusual weight loss, fatigue, weakness, etc.
Risk factors associated with a disease
Lot of research has been undergone, to evaluate the risk factors associated with the conditions, some of them can be noted as; genetic link ups, smoking, family history of live births, early life exposures to harmful toxins, obesity, etc.
RA is being diagnosed through systematic symptomatic review, family history, conduction of physical examination for the better determination of deformities, etc. However, it has been identified that the ailment, if diagnosed in a very early phase, then there are fare chances of its delayed progression. Although, conventional medical treatment may offer anti-inflammatory dosage; it is surveyed that long term consumption of these steroidal medicines can give rise to other complications, associated with the conditions, like heart diseases, kidney problems, etc. Contrary to which, the recent advances in a science of regenerative medicines, like stem cells therapy has been found to be an effective alternative to decrease the progressive damage of the tissue, along with regeneration of lost as well as damaged cells leading to their functional restoration.
Other complications associated with the conditions
A thorough understanding of the ailment has suggested many physical, mental as well as social consequences that have severely affected lives of many individuals, causing pain, disability, mental disturbances, as well as premature deaths; however, some of the major co-morbidities associated with the condition, can be considered as cardiovascular disorders, diabetes, kidney disorders, etc.
It has been estimated that people with rheumatoid arthritis, can face higher risk of developing heart diseases, diabetes, psychological issues, etc. in order to prevent such kind of complications, a treatment plan should as well be emphasized on managing these comorbidities.
Prevalence of Disease
Statistical analysis has suggested that from the year 2013-15, more than 55 million people are affected with the condition, annually in many developed countries. While amongst more than 100 different forms of arthritis, osteoarthritis is known to be the most prevalent, other common conditions may include rheumatoid arthritis. Next 20 years’ statistical data shows a dramatic improvement, i.e. almost 80 million people, estimated to be suffering with the ailment. The survey is as well suggesting that the risk of arthritis is 20 % more for women than men.
The statistical analysis of last couple of years has suggested that 8% people are within the age group of 18-44, 30% confirmed cases are within the age group of 45-65; whereas out of the total reported cases of arthritis, 30% are being categorized under obese group and 23% are being categorized under overweight.
As far as the statistical data pertaining to the disabilities, arthritis and other rheumatoid conditions are reported to be disabling more than 44% affected people; through various channels of activity limitations.
The data further implies a huge, disproportionate economic burden, the world is facing and hence necessitates further requirement of scientific advancements and acceptance to updated technology.