A new therapy that cuts off the way some cancer cells communicate significantly slows the rapid spread of a common and deadly brain tumor, help new research has found.

Glioblastoma is the most common brain tumor in adults and there is no effective long-term treatment and patients usually live for 12 to 15 months after diagnosis, discount according to the US National Cancer Institute.

“The technique improved the survival time for patients with glioblastoma by 50 percent when tested in a mouse model, sick ” said Loic Deleyrolle, research assistant professor of neurosurgery in the University of Florida College of Medicine in the US. The researchers focused on disrupting the cell-to-cell communication that allows cancer stem cells to spread. To do that, they targeted a channel that cancer cells use to transfer molecules. By cutting off their communications pathway, the deadly cells stay in check, Deleyrolle said.

The research focused on connexin 46, a protein that is an essential component of cancer stem cells. Connexin 46 is part of intercellular channels known as a gap junction. That intercellular channel, which allows cells to exchange molecules and ions, is crucial to the growth of a glioblastoma tumor, researchers found.

“When we shut down those channels in the cancer stem cells, we can significantly reduce the tumor-forming abilities of the cells,” Deleyrolle said. While the technique has yet to be tested in humans, Deleyrolle said the implications are clear and relevant.

The study was published recently in the journal Cell Reports.

Source : TimesofIndia


A-102, Sector-V Noida-201301, UP, India

Tel: +91-9654321400

Email: info@advancells.com 



Partner With Us

Newsletter Subscription

"Subscribe to our newsletter, its free"




"Advancells is a strong advocate of greater transparency in medical procedures in general and Stem Cells Procedures in particular. As a part of our effort of bringing transparent procedures to our clients, we provide each client a Third Party Certificate (from an internationally accredited lab) for the cell count and viability of the cells that we are able to process from the autologous cell source of the patient. To view the sample copy of the certificate  "click here"



By Advancells. Copyright 2020. All Rights Reserved. All images and content used in this site are original. Any attempt to copy will come under criminal jurisdiction.