Stem cells called the 'future of medicine' have amazing qualities apart from being the potential candidates for treating many deadly diseases. This unique quality of stem cells have left us to wonder “How can a group of cells; descending from a single original cell is used to treat diseases?” Well, the answer lies in the mechanism of how stem cells work!
Though the science does not have a complete answer to this question, but certainly it has a rationale. There are lot of evidences from the accumulated research and clinical data that these are the “Creator Cells” i.e. they have the potential to develop most of the cells of the body.
They are undifferentiated cells lying dormant in the body. At the time of injury these cells are activated by the intricate molecular machinery and signalling mechanism, which will regulate their fate. Apart from being differentiated to specialized cells thus regenerating a tissue; these cells are also function as “Bricks”. Bricks those are capable of excreting certain signals that bring the brick mason and general contractor to the repair. This phenomenon is called as paracrine effect. With the help of cell to cell signalling these cells secrete certain chemicals such as growth factors, hormone, cytokines which act as controlling devices to orchestrate the repair job.
Intrinsic messaging between stem cells is basically a key to activate series of cellular pathways thereby repairing the cells and acting as a stimulant to replace damaged cells. Thus giving rise to the most important benefit of stem cells i.e. 3R’s i.e. Regeneration, Repair and Rejuvenation.
Though stem cells are small but they are certainly smart...