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Stem Cell Treatment for Autism

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    Stem Cell Treatment for Autism Spectrum Disorder

    We are ready with our advanced secretome tool to combat innate and adaptive immune responses and other abnormal immune system alterations evident in Autism Spectrum Disorder

    Autism Spectrum Disorder is a very intrigued term, sheltering a number of other neurodevelopmental disorders like Autism, Rett Syndrome, Asperger’s syndrome, Childhood Disintegrating Disorders etc. It includes some enigmatic conditions that have their origin in altered cellular interactions and environmental factors; during embryonic development. Unfortunately, statistical analysis has witnessed the increased prevalence of ASD; still, there are no effective drugs to manage its core symptoms. The advent of stem cell Treatment for Autism Spectrum Disorder has presented a new hope to repair the root cause of its development. The basis of all previous scientific studies involving stem cells largely comes from harnessing the inherent potential of stem cells to repair, regenerate and modulate (Caplan & Dennis, 2006). Stem cells naturally secrete cytokines and other growth factors that modulate the inflammatory response in the brain, avoiding further damage to its networking abilities (Sacai et.al, 2020). These properties controlling your are making stem cells, extremely attractive candidates for brain developmental issues. Other studies have shown the ability of stem cells to repair the upset connection between the neurons seen in Autism Spectrum Disorders (Perets et.al., 2018). Thus, the research opens up safer possibilities for treating ASD.

    Stem Cell Autism Treatment : Advancells Protocols

    As more and more studies are published supporting stem cell therapy for ASD, there are yet several things to consider when you are contemplating treatment using any of the acknowledged stem cell sources. Broadly, it is important to learn about the type of stem cell used in the therapy, whether autologous stem cell therapy or allogeneic stem cell therapy.
    At Advancells, with our advanced technical support, scientific excellence and competent quality management system; we are able to offer a comprehensive personalized therapeutic solution, as per individualized requirements. We have acquired expertise over isolation of stem cells from Bone Marrow, Adipose Tissue as well as Umbilical Cord Derived Wharton’s Jelly.

    Procedure of Treatment of Autism through Stem Cells Therapy

    Treatment Qualification

    Source Extraction

    Processing of stem cells

    Re-infusion

    Limited facial expressions
    Difficulty sustaining friendships
    Unusual sensitivity
    Obsessions
    Hyperactivity
    Aggression
    Atypical social behavior
    Poorly developed speech skills
    Avoids eye contact
    High-pitched or flat voice
    Difficulty with transitions
    Repetitive behaviours
    Slowed growth
    Abnormal hand movements
    Breathing problems
    Seizures
    Problems in muscles coordination
    Irritation and Stress
    Regressive motor skills
    Poor bowel control
    Restricted behaviours
    Lack of emotions
    No social skills
    Lack of self-care
    Repeating words
    Unresponsive
    Avoiding physical contact such as hugs
    Apathy to activities
    Anger issues
    No interest in sharing emotions
    Studies have indicated that the

    Studies have indicated that the cause of autism spectrum disorder has not been identified yet. In fact, researchers have pinpointed the combination of genetic, environmental factors responsible for the same.

    • Fetal presentation in the womb, multiple births, increased maternal age
    • Fetal distress, birth injury, hypoxia during birth, trauma along with neonatal anaemia
    • Multiple births increased maternal age and/or viral infection during gestation
    • Metabolic imbalance, immune dysfunction along with RH incompatibility
    • Rare maternal diseases like hyperbilirubinemia, liver dysfunction
    • Long term exposure to heavy metals & toxin exposure like mercury
    • Intrauterine exposure to viral infections like rubella, CMV and hepatitis
    • Genetic predisposition, epigenetic alterations and X-linked fragile syndrome
    • Other environmental factors like lifestyle changes, ageing during pregnancy

    “If it’s an autism, waiting for your child to catch on his own isn’t a solution; you need to act early to see a better version of your baby”

    An increasing prevalence of neurodevelopmental issues has helped raise drastic awareness among parents. As it is very important for you to act early if any of the symptoms or relative developmental issues are noted. Our supportive therapy for autism is made to get maximum benefits. As per the guidelines published by the American Academy of Paediatrics (AAP), some of the proven therapies are
    Occupational Therapy It effectively helps children to work on physical, motor and cognitive skills. The goal is to achieve control over everyday skills by becoming more independent and involving active participation. It can also help strategize sensory issues post stem cell therapy.
    Hyperbaric Oxygen TherapyIt provides a higher concentration of oxygen delivered in a chamber with higher atmospheric pressure. The condition initiates hypoxia in the brain to facilitate improved oxygenated blood flow towards the brain, hence indirectly improving the flow of stem cells towards the target.
    Speech TherapyIt addresses challenges with language and communication. It helps children with autism to improve verbal, non-verbal and social communication. The goal is to help children improve communication skills in more functional ways.
    Applied Behavioural AnalysisIt is an evidence-based holistic approach, widely accepted to enhance the functional abilities of children under Autism Spectrum Disorder. It incorporates a multidisciplinary treatment approach targeting social communication, behavioural issues, cognitive abilities and parent-mediated interventions in order to achieve overall improvements.
    Play TherapyIt is something akin to floortime therapy; specifically designed to develop interest and/or obsession amongst children under Autism Spectrum Disorder for developing social interaction through a play-way method. It incorporates strategic use of play techniques to allow youngsters to share their feelings, emotions with their parents and/or siblings.
    Sensory IntegrationThe therapy is specifically designed to enhance processing skills of sensory information; such as textures, sounds, smell, taste, brightness etc. With the rationale of understanding how information is being processed in their brain, children are helped to make better sense of information that can be used in doing multiple tasks on a daily basis.
    Dietary ModificationFor some children with autism, certain dietary changes have reportedly produced dramatic differences in the symptomatic exhibition and functional improvements. With good scientific investigation, experts believe that children with autism are to be evaluated for certain dietary modifications, either in combination or alone; in order to evaluate significant functional improvement in the brain.
    Psychological InterventionsIt aims at shaping behavioural issues using classic and/or instrumental conditioning. It is designed with objectives to focus mainly on core deficits associated with mental issues or psychological challenges reported in the spectrum.

    In order to ensure the quality and effectiveness, we follow a safety evaluation system, based on the existing regulatory guidelines and advanced testing techniques.

    • Each batch of cells is tested for gram testing at different levels of processing to avoid contamination
    • Cells are characterized for markers, specific for cell type; to make sure that the right cells are given
    • The stem cell source is tested for infectious diseases; to limit the spread of infection.
    • The Final wash of stem cells source is tested for aerobic as well as anaerobic bacteria to avoid contamination
    • The media in which the cells are being grown is tested for gram bacteria and mycoplasma analysis
    • Each batch of cells is tested for endotoxin and passed only if within the limit
    • The karyotyping analysis is performed for each batch to observe mutational changes
    • Cells are counted with an automated cell counter, the reports of which are provided with each batch
    • We provide a “Certificate Of Analysis” for each batch of cells; to make sure that the quality is being maintained

    Research has emphasized that adult stem cell therapy is absolutely safe form of treatment; although a lot of clinical development and refinement are on the way. The outcome obtained from clinical studies is remarkably positive and motivating. With rigorous data analysis, we propose a reversal and multimodal treatment showing clinical improvements in Autism through stem cell therapy.

    Worldwide Clinical Studies using Stem Cells obtained from different sources

    Improvement in clinical signs and symptoms
    TYPES

    Limited facial expressions
    Limited facial expressions

    Difficulty sustaining friendships
    Difficulty sustaining friendships

    Unusual sensitivity
    Unusual sensitivity

    Obsessions
    Obsessions

    Hyperactivity
    Hyperactivity

    Aggression
    Aggression


    Atypical social behavior
    Atypical social behavior

    Poorly developed speech skills
    Poorly developed speech skills

    Avoids eye contact
    Avoids eye contact

    High-pitched or flat voice
    High-pitched or flat voice

    Difficulty with transitions
    Difficulty with transitions

    Repetitive behaviours
    Repetitive behaviours


    Slowed growth
    Slowed growth

    Abnormal hand movements
    Abnormal hand movements

    Breathing problems
    Breathing problems

    Seizures
    Seizures

    Problems in muscles coordination
    Problems in muscles coordination

    Irritation and Stress
    Irritation and Stress


    Regressive motor skills
    Regressive motor skills

    Poor bladder control
    Poor bladder control

    Restricted behaviours
    Restricted behaviours

    Lack of emotions
    Lack of emotions

    No social skills
    No social skills

    Lack of self-care
    Lack of self-care


    Limited facial expressions
    Regressive motor skills

    Difficulty sustaining friendships
    Poor bowel/bladder control

    Unusual sensitivity
    Restricted behaviours

    Obsessions
    Lack of emotions

    Hyperactivity
    No social skills

    Aggression
    Lack of self-care

    CAUSES
    Studies have indicated that the cause of autism spectrum disorder has not been identified yet. In fact, researchers have pinpointed the combination of genetic, environmental factors responsible for the same.

    • Fetal presentation in the womb, multiple births, increased maternal age
    • Fetal distress, birth injury, hypoxia during birth, trauma along with neonatal anaemia
    • Multiple births increased maternal age and/or viral infection during gestation
    • Metabolic imbalance, immune dysfunction along with RH incompatibility
    • Rare maternal diseases like hyperbilirubinemia, liver dysfunction
    • Long term exposure to heavy metals & toxin exposure like mercury
    • Intrauterine exposure to viral infections like rubella, CMV and hepatitis
    • Genetic predisposition, epigenetic alterations and X-linked fragile syndrome
    • Other environmental factors like lifestyle changes, ageing during pregnancy
    SUPPORTIVE THERAPY

    “If it’s an autism, waiting for your child to catch on his own isn’t a solution; you need to act early to see a better version of your baby”

    An increasing prevalence of neurodevelopmental issue has helped raise drastic awareness among parents. As it is very important for you to act early, if any of the symptoms or relative developmental issues are noted. Our rehabilitative programs for kids with autism are made to get maximum benefits. As per the guidelines published by the American Academy of Paediatrics (AAP), some of the proven therapies are:

    Limited facial expressions
    Occupational Therapy

    Limited facial expressions
    Occupational Therapy

    Limited facial expressions
    Occupational Therapy

    Limited facial expressions
    Occupational Therapy

    Limited facial expressions
    Occupational Therapy

    Limited facial expressions
    Occupational Therapy

    Limited facial expressions
    Occupational Therapy

    Limited facial expressions
    Occupational Therapy

    QUALITY CONTROL

    In order to ensure the quality and effectiveness, we follow a safety evaluation system, based on the existing regulatory guidelines and advanced testing techniques.

    • Each batch of cells is tested for gram testing at different level of processing to avoid contamination
    • Cells are characterized for markers, specific for cell type; to make sure that right cells are given
    • The stem cell source is tested for infectious diseases ; to limit the spread of infection.
    • The Final wash of stem cells source is tested for aerobic as well as anerobi bacteria to avoid contamination
    • The media in which the cells are being grown is tested for gram bacteria and mycoplasma analysis
    • Each batch of cells is tested for endotoxin and passed only if within the limit
    • The karyotyping analysis is performed for each batch to observe mutational changes
    • Cells are counted with automated cell counter, the reports of which are provided with each batch
    • We provide ” Certificate Of Analysis” for each batch of cells; to make sure that the quality is being maintained
    IMPROVEMENTS

    Research has emphasized that adult stem cell therapy is absolutely safe form of treatment; although a lot of clinical development and refinement are on the way. The outcome obtained from clinical studies is remarkably positive and motivating. With rigorous data analysis, we propose a reversal and multimodal treatment showing clinical improvements in Autism through stem cell therapy.

    Worldwide Clinical Studies using Stem Cells obtained from different sources

    Improvement in clinical signs and symptoms

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    Statistics of Overall Improvement of Autism through Stem Cell Therapy

    We understand that Autism is not a single disorder but has more than a hundred other variations, commonly grouped as autism spectrum disorders. Under this umbrella term, every child has a distinct set of strengths and challenges and needs to be tackled individually.

    Today’s era of personalized medicine has put forth a prospective approach based on the unique capacity of stem cells to positively influence the cellular communication, growth, regeneration, and restoration of damaged cells as well as the immune system. We are focused to provide a comprehensive personalized therapeutic solution, best suited for the individual requirements of children undergoing treatment for ASD.

    Download the brochure to understand in depth knowledge about Autism Spectrum Disorder.

    Autism FAQs

     
    Advancells is a strong advocate of greater transparency in medical procedures in general and Stem Cells Procedures in particular. As a part of our effort of bringing transparent procedures to our clients, we provide each client a Third Party Certificate (from an internationally accredited lab) for the cell count and viability of the cells that we are able to process from the autologous cell source of the patient. To view the sample copy of the certificate  click here

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