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Critical Limb Ischemia Treatment

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    Stem Cell Treatment For Critical Limb Ischemia

    Critical Limb Ischemia is the condition with chronic ischemic at-rest pain that may progressively lead to severe skin ulcers, gangrene, or limb loss. The condition is typically related to the objectively proven severe blockage in the artery. The disease implies, chronicity and is usually associated with multiple sites of arterial obstruction that severely reduced blood flow to the tissues. The disease is clinically manifested as rest pain, non healing wounds and/or tissue necrosis.
    Ischemic pain can be associated with the burning sensation in the ball of the foot and toes, which can be worsened at night may be because of the loss of gravity assisted flow to the foot. In the past few years the most significant change in critical limb ischemia treatment has been the increasing tendency to shift from bypass surgery to less invasive stem cell therapy for critical limb ischemia as first-choice causing revascularization of the damaged tissue and removal of plaque deposits to a certain extent.

    Critical Limb Ischemia Symptoms

    Major Manifestations of CLI, in patients include the following:

    • Pain in the legs and feet when the person is at rest and not moving (also called “ischemic rest pain”)
    • Sores or infections on the legs and feet that won’t heal
    • Faint or absent pulse in the leg or foot below the blockage

    Stem Cells Therapy for Critical Limb Ischemia Treatment: Advancells Protocol

    Stem cell treatment at Advancells involves exploitation of the most potent stem cells isolated from patients own Bone marrow or Adipose tissue or may be both depending upon the assessment. Our top priority is to provide very comprehensive, individualized treatment pattern which is best suited for the patients undergoing stem cell treatment for critical limb ischemia. With extensive research these challenges are now comprehensible to therapeutic ventures resulting in new treatments of critical limb ischemia using autologous treatment/allogenic transplant for adipose-derived mesenchymal stromal cells treatment and bone marrow stromal cells treatment. This new insight on the treatment of critical limb ischemia has helped in identifying the potential to overcome critical limb ischemia with stem cells, primarily using autologous stem cell transplant in form of hematopoietic stem cell transplant or mesenchymal stromal cells treatment.

    Stem Cell Treatment for Critical Limb Ischemia at Advancells is divided into 4 Steps

    Treatment Qualification

    Source Extraction

    Processing of stem cells


    CAUSES OF Critical limb ischemia


    peripheral artery disease

    high blood pressure

    Family history


    SYMPTOMS OF Critical limb ischemia

    Pain or numbness in the feet

    Thickening of the toenails

    Absent pulse in the legs or feet

    Open sores, skin infections or ulcers

    Dry gangrene of the legs or feet

    Why Choose Stem Cell Therapy?

    100% Safe

    Targeted delivery






    Must Read Articles on Critical Limb Ischemia

    The Critical Limb Ischemia: The silent killer
    The Critical Limb Ischemia: The silent killer

    Chronic Limb Ischemia is the most severe form of peripheral artery disease, characterized by blocked arteries and poor supply of oxygenated blood, to the extremities, such as arms and legs. Although initial symptoms are very subtle, through some of the general...

    Chronic Critical Limb Ischemia: Diagnosis And Treatment
    Chronic Critical Limb Ischemia: Diagnosis And Treatment

    What is Critical Limb Ischemia? Limb ischemia refers to obstruction of the arteries leading to reduced flow of blood to the limbs (hand, arms and feet). It is categorized into Acute Limb Ischemia (ALI) or Critical Limb Ischemia (CLI) depending on the severity or...

    Critical Limb Ischemia – A Life Crippling Ordeal
    Critical Limb Ischemia – A Life Crippling Ordeal

    Imagine waking up in the middle of the night from burning pain in legs. Even worse, it is aggravated at resting position and relieved only by sitting or standing. A dreadful dream isn’t it? This exactly describes the suffering of a patient with Critical Limb Ischemia...

    Statistics of Overall Improvement of Critical Limb Ischemia through Stem Cell Therapy

    Advancells is a strong advocate of greater transparency in medical procedures in general and Stem Cells Procedures in particular. As a part of our effort of bringing transparent procedures to our clients, we provide each client a Third Party Certificate (from an internationally accredited lab) for the cell count and viability of the cells that we are able to process from the autologous cell source of the patient. To view the sample copy of the certificate  click here