Stem Cell Therapy For Diabetes
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Stem Cell Treatment for Diabetes Mellitus
Diabetes Mellitus is a common yet chronic autoimmune disease. Despite its high mortality and morbidity rate, it is often ignored for being less severe. However, if ignored for a long time, it may turn out to be fatal. Studies have indicated that adults with chronic diabetes are at higher risk of heart attacks and strokes. Diabetic neuropathy increases the chances of infection, ulcers, and the eventual need for limb amputations. Similarly, diabetic retinopathy is the primary cause of blindness, occurring as a result of chronic accumulated damage to the small blood vessels. Current treatment of diabetes involves diet, and physical activity, along with other interventions to prevent and manage diabetes mellitus; however, stem cell treatment for diabetes has practically fulfilled the promise of functional restoration to the great extent. With a combinational approach using stem cell therapy along with exosomes, it is possible to keep excessively high glucose levels under check.
Stem cell Therapy for Diabetes Mellitus: Advancells Protocol
With the extensive research conducted in the last couple of decades, it can be confirmed that stem cell therapy holds immense potential for treating diabetes mellitus and reducing the insulin dependency of patients with chronic DM. Various studies have confirmed the differentiation potential of mesenchymal stem cells into pancreatic islet cells through a thorough understanding of intricate signal transduction mechanisms and developmental stages. As a consequence of which, multiple ongoing successful clinical trials have now confirmed it to be a realistic treatment for diabetes mellitus. The early results of these clinical trials using mesenchymal stem cells are very promising, confirming 70% of the participants reported reduced or absolutely zero insulin dependency within one year of stem cell infusion, directly into the hepatic portal vein. Although, researchers are looking for more optimized protocols for refined treatment outcomes; in the currently available therapeutic interventions, stem cells along with exosomes can be a highly reliable alternative to reduce long-term insulin dependency and multiple organ damage.
Procedure of Treatment of Diabetes through Stem Cells Therapy
Treatment Qualification
Source Extraction
Processing of stem cells
Re-infusion
Accordingly, certain causes of Diabetes Mellitus include:
DIABETES MELLITUS
- You are more likely to develop type 2 diabetes if you are sedentary and overweight.
- Type 2 diabetes is generally a result of insulin resistance, wherein muscles, liver as well as fat cells do not use the insulin that is produced by the body.
- As in the case of type 1 diabetes, certain genes are more susceptible to insulin resistance or functional dysfunction of pancreatic beta cells. That is why, the disease tends to run in families and is more common in certain ethnic/racial groups like American Indians, African Americans, Hispanics/Latinos, Pacific Islanders, etc.
- Studies have confirmed that gestational diabetes, a type of diabetes that predominantly develops during pregnancy is mostly caused due to hormonal changes and changes in the inflammatory profile of the body; especially along with genetic susceptibility and lifestyle changes.
- Gestational diabetes is also associated with insulin resistance, due to hormones produced during the formation of the placenta.
- Genetic mutations are also identified to be responsible for insulin resistance and pancreatic dysfunction, especially observed during monogenic diabetes.
- Other life-threatening conditions like cystic fibrosis that cause pancreatic scarring are also observed to be responsible for type 2 diabetes due to insufficient production of pancreatic beta cells.
- Pancreatitis, pancreatic cancer, and trauma can harm the production of pancreatic beta cells or make them less available to produce insulin; further causing diabetes mellitus.
- Certain types of medicines like niacin, diuretics, anti-seizure drugs, psychiatric drugs, and drugs to treat certain viral infections like HIV, and COVID-19 are believed to be responsible for pancreatic damage; further causing diabetes mellitus.
and body. Several studies have indicated the role of yoga in managing many chronic diseases including diabetes mellitus, obesity, and asthma. Studies have indicated that the implementation of yoga in routine life can prevent diabetes.
As discussed previously, various studies have confirmed how a combination approach using stem cell therapy and exosomes is highly effective in minimizing inflammation and regularizing immune factors to support *-the functional restoration of the pancreas and other major organs. Accordingly, the assessments done based on extensive data collected from a large number of clinical investigations have proven that
-
Best Treatment for Diabetes with Autologous Stem Cells
Patients from across the world have approached Advancells for stem cells based regenerative therapies. By providing quality regenerative therapies for our patients, we are glad we have been able to improve the quality of life for more than 8000 patients. Find out how Stem Cell Therapy is improving the lives of patients suffering from Diabetes.
TYPES OF DIABETES MELLITUS
CAUSES
LIVER DISORDER
- You are more likely to develop type 2 diabetes if you are sedentary and overweight.
- Type 2 diabetes is generally a result of insulin resistance, wherein muscles, liver as well as fat cells do not use the insulin that is produced by the body.
- As in the case of type 1 diabetes, certain genes are more susceptible to insulin resistance or functional dysfunction of pancreatic beta cells. That is why, the disease tends to run in families and is more common in certain ethnic/racial groups like American Indians, African Americans, Hispanics/Latinos, Pacific Islanders, etc.
- Studies have confirmed that gestational diabetes, a type of diabetes that predominantly develops during pregnancy is mostly caused due to hormonal changes and changes in the inflammatory profile of the body; especially along with genetic susceptibility and lifestyle changes.
- Gestational diabetes is also associated with insulin resistance, due to hormones produced during the formation of the placenta.
- Genetic mutations are also identified to be responsible for insulin resistance and pancreatic dysfunction, especially observed during monogenic diabetes.
- Other life-threatening conditions like cystic fibrosis that cause pancreatic scarring are also observed to be responsible for type 2 diabetes due to insufficient production of pancreatic beta cells.
- Pancreatitis, pancreatic cancer, and trauma can harm the production of pancreatic beta cells or make them less available to produce insulin; further causing diabetes mellitus.
- Certain types of medicines like niacin, diuretics, anti-seizure drugs, psychiatric drugs, and drugs to treat certain viral infections like HIV, and COVID-19 are believed to be responsible for pancreatic damage; further causing diabetes mellitus.
SUPPORTIVE TREATMENT
Diabetes Mellitus is a metabolic disorder characterized by hyperglycemia, and abnormal lipid and protein metabolism. This scavenger disease is responsible for many long-term complications like diabetic neuropathy, diabetic retinopathy, cardiovascular disorders, kidney damage, etc. Thus, it has a significant impact on the quality of life. The consensus on the treatment of type 2 diabetes is that it can be managed through disciplinary changes in diet and lifestyle; however, certain alternative therapies like stem cell therapies administered in combination with exosomes are recently observed to be potent enough in managing diabetes mellitus along with avoiding its long-term complications. Accordingly, a holistic approach offering regenerative medicine along with rehabilitation and lifestyle changes is suggested for the effective regulation of glucose metabolism.
OUTCOMES
As discussed previously, various studies have confirmed how a combination approach using stem cell
therapy and exosomes is highly effective in minimizing inflammation and regularizing immune factors to support *-the functional restoration of the pancreas and other major organs. Accordingly, the assessments done based on extensive data collected from a large number of clinical investigations have proven that
TESTIMONIAL
-
Best Treatment for Diabetes with Autologous Stem Cells
Patients from across the world have approached Advancells for stem cells based regenerative therapies. By providing quality regenerative therapies for our patients, we are glad we have been able to improve the quality of life for more than 8000 patients. Find out how Stem Cell Therapy is improving the lives of patients suffering from Diabetes.
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Role of Stem Cells in Fat Metabolism to Manage Diabetes
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Meta-analysis of Diabetes Mellitus Injury using stem cell therapy
Several clinical investigations have confirmed that stem cell and exosome therapy is safe and effective for patients with chronic diabetes mellitus. The meta-analysis was done based on 10 clinical investigations and one in-house study suggested that stem cells when administered along with exosomes through a pancreatic vein, showed significant improvement in HbA1C levels. Studies have also confirmed reduction in creatinine and reduced dependency on insulin.
Regulated Sleep Patterns
Regulated Blood Glucose levels
Improved Metabolism
Decreased HbA1C
Reduction in Insulin Dependency
FAQs
Type 2 diabetes is a more common form of the disease and is different from type 1 diabetes. In type 1 Diabetes, which is most common in young children also known as Juvenile Diabete, the body is not able to produce insulin, which is required for glucose metabolism. Whereas type 2 diabetes is more common in adults, wherein the insulin, which is produced by the body, is not able to metabolize blood glucose. Whether you are insulin resistant or have too little insulin the end result is the high blood glucose level.
The disease develops gradually and some of the common symptoms associated with the disorder are fatigue, extreme thirst, frequent urination, extreme hunger, weight loss, frequent infection, slow wound healing, blurry vision.
Undifferentiated adult autologous stem cells are mutable and can metamorph into a countless number of cells as per the requirement. This remarkable property of stem cells can be exploited for treating a variety of diseases. These cells can be isolated from the most potent sources of our own body known as Adipose Tissue and Bone Marrow. Upon implanting back into the body, these cells can rapidly multiply with the great speed to restore damaged cells, set up a microenvironment that can stimulate the secretion of growth factors, cytokines as a booster for regeneration.
Conventional treatment approach involves hormone therapies which were again associated with many side effects. Long-term use of steroids is also dangerous for welcoming many diseases. Additionally, if left untreated for a longer period of time, it can also give rise to diabetic foot, kidney damage and other physical problems.
Please go through, our treatment brochures for other Diabetes related information.
Advancells is a strong advocate of greater transparency in medical procedures in general and Stem Cells Procedures in particular. As a part of our effort of bringing transparent procedures to our clients, we provide each client a Third Party Certificate (from an internationally accredited lab) for the cell count and viability of the cells that we are able to process from the autologous cell source of the patient. View sample Certificate
