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Stem Cell Therapy for Multiple Sclerosis

With Our unique

NanoRegen Complex

Our patients can improve flexibility, strength, mobility, and basic motor functions.

Stem cell Therapy for Multiple Sclerosis

A complex degenerative disorder of the central nervous system is characterized by long-term progressive loss of axons. It is identified to be an autoimmune disease, attacking the central nervous system and damaging nerve fibers; further making it very hard for the brain to “talk” with the rest of the body. Several medications, currently offered to manage symptoms of multiple sclerosis are reported to cause serious side effects and may stop working over a period of time. With the option of regenerative medicine, 69-70% of people with MS can manage gracefully its symptoms as well as delay progression and relapse.

Stem Cell Treatment for Multiple Sclerosis: Advancells Protocol

The current success in managing MS depends largely on the regulatory action of the adaptive immune system; which is identified to be a key driver of disease pathogenesis. Mesenchymal stem cells, when administered along with their own exosomes can work to prevent acuter inflammatory insults by limiting the infiltration of activated T cells, B cells, and macrophages. Due to the same, these cells cannot further contribute to the demyelination leading to progressive loss of axons. Although, more in-depth clinical understanding and a clear rationale of use are still needed; currently, stem cells and exosomes are identified to be the best available treatment option for a quality life.

Stem cell Therapy for Multiple Sclerosis: Advancells Protocol

Treatment Qualification

Source Extraction

Processing of stem cells

Re-infusion

MULTIPLE SCLEROSIS THERAPY
STEM CELLS PROCEDURE
RESULTS
Studies have discovered that mesenchymal stem cells and their exosomes can significantly increase myelin content, oligodendrocyte precursor cells, and neural stem cell levels. They are also identified to reduce oxidative stress in hippocampal slice culture, leading to delayed progressive degeneration. Based on these observations, we propose the adjunct use of exosomes along with mesenchymal stem cells to stimulate remyelination for patients with different types of multiple sclerosis, like
Frequent Falls
Dysesthesia
Wadding Gait
Extreme Fatigue
Large Calf Muscles
Loss of balance
Delayed Growth
Numbness, tingling sensation
Muscle Pain
Visual Problem
Stiffness
Vertigo/Dizziness
Trouble seeing
Trouble seeing
Increased sensitivity to heat
Increased sensitivity to heat
Numbness in the feet
Numbness in the feet
Depression
Depression
Difficulty in clear thinking
Difficulty in clear thinking
Frequent urination
Frequent urination
Muscle spasm
Muscle spasm
Extreme pain like headache, pain in legs and feet
Extreme pain like headache, pain in legs and feet
Muscular weakness
Muscular weakness
Trouble maintaining balance
Trouble maintaining balance
Visual problem
Visual problem
Paralysis
Paralysis
Extreme fatigue
Extreme fatigue
Numbness, tingling sensation
Numbness, tingling sensation
Difficulty walking and coordination
Difficulty walking and coordination
Problem with cognition
Problem with cognition
Bowel and bladder issues
Bowel and bladder issues
Difficulty in walking and coordination
Difficulty in walking and coordination
Extreme tiredness
Extreme tiredness
Muscle spasm
Muscle spasm
Visual loss
Visual loss
Memory trouble
Memory trouble
Problem focusing
Problem focusing
Vertigo
Vertigo
Experts are still trying to understand the exact mechanism to know the underlying cause of multiple sclerosis, although a lot is understood so far, thanks to the intense research going on worldwide. Factors that may trigger the sudden onset of MS are:
Causes-of-muscular-dystrophies

CAUSES OF
MUSCULAR DYSTROPHIES
  • Exposure to certain viruses and bacteria like Epstein-Barr Virus can trigger MS later in life.
  • Environmental susceptibility also plays a very important role in managing epigenetic changes.
  • Lack of sufficient vitamin D is identified to be a risk factor for multiple sclerosis.
  • It is an autoimmune disorder and hence, the abnormal immune response can cause inflammation and damage to the central nervous system.
  • Certain studies have confirmed that obesity increased the risk of later developing MS.
  • Many viruses and bacteria including measles, canine distemper.
The stem cell therapy administered in combination with exosomes can be an effective alternative to regularize immune inflammation in the body, a primary cause of multiple sclerosis. Along with immunomodulatory therapies to regulate underlying immune disorders specifically directed toward reducing the episodes of relapse; rehabilitative support is also identified to be necessary to delay the progressive degeneration of brain mass. Accordingly, we have compiled a series of rehabilitation programs to get symptomatic benefits for Multiple Sclerosis.
Hyperbaric Oxygen Therapy
Hyperbaric Oxygen Therapy Recently, multiple studies have confirmed the advantages of ozone therapy or hyperbaric oxygen therapy. With more supply of oxygen to the brain, these therapies reduce brain damage and functional loss. Also, during treatment due to increased atmospheric pressure, the brain goes into a hypoxic state for some time, redirecting stem cells toward the brain at a faster rate. The therapy has been very effective if taken immediately post-infusion.
Hydrotherapies
HydrotherapiesAs per our database, a series of water-based exercises can significantly reduce pain intensity in people with Multiple Sclerosis. Some studies have also noted benefits in managing depression in people suffering from multiple sclerosis. Some researchers are also using Ai Chi, a water-based version with benefits like stress management, posture control, body awareness, strength as well as balance.
Physiotherapy
PhysiotherapyGeneral physiotherapy sessions are helpful in managing certain symptoms of MS, through improved fitness, stamina, strength, and flexibility. In addition to the same, physiotherapy has also proven to be beneficial for regulating mood swings, raising self-esteem, increasing muscle size, and preventing joint contracture.
Cooling/Lowering of Body Temperature
Cooling/Lowering of Body Temperature Transient cooling of body temperature while using suitable cold packs or taking cold baths is suggested for patients with multiple sclerosis. This may improve postural stability, muscle strength of the legs, fatigue, and gait. Studies have also suggested the use of cooling garments to increase functional attributes and stamina.
Drug Treatment
Drug TreatmentDepending upon the stage of development of degeneration, our experts can suggest specific drugs like corticosteroids, baclofen, etc. can be offered as multimodal treatment like reducing neurogenic bladder dysfunction.
Occupational Therapy
Occupational TherapyOccupational therapy can be proposed for tonus regulation, reduction of muscular fixation, training of sensory skills, as well as coordination of movements. Our data suggest that there can be a significant reduction of tremor intention after the short-term application of local ice.

Various studies have confirmed that stem cell therapy has proposed promising improvement, thus attracting the attention of researchers as an alternative treatment for people with MS. Also, it should be noted that there is no complete cure for multiple sclerosis. Even conventional therapeutics are offering steroids in the form of capsules, which can delay the progression, contrary to which an alternative medicine can reduce progressive damage of brain cells, improve functional attributes and promote the regeneration of new cells. During clinical analysis, it was observed that

Worldwide Clinical Studies using Stem Cells obtained from different sources

60% people have reported increased survival functions on an average with 87.76 months

  • Multiple Sclerosis

    With the advent of anti-inflammatory properties of stem cells, the science of regenerative medicine has opened new avenues for treating auto-immune disorders like Multiple Sclerosis. Researchers are supporting the idea of delaying the disease progression and repairing the damage caused due to loss of neuronal contact and cellular communication, on the basis of large data gathered from different pre-clinical as well as clinical investigations. Stem cells, isolated from different sources of the human body and coaxed in the laboratory setting to reduce autoimmune-associated inflammation, will soon be considered as the mainstream treatment for fatal, progressive auto-immune disorders like Multiple Sclerosis. Still, a lot needs to be explored on configuring effective pathways for their communication to standardize their therapeutic outcome instead of relying on the steroidal medications, which can trigger damage to other vital organs of the body. Stem Cell Therapy for Multiple Sclerosis can be considered as a safe and viable option, effective in stopping the progression and increasing overall life expectancy.

MULTIPLE SCLEROSIS
TYPES

Limited facial expressions
Limited facial expressions

Difficulty sustaining friendships
Difficulty sustaining friendships

Unusual sensitivity
Unusual sensitivity

Obsessions
Obsessions

Hyperactivity
Hyperactivity

Aggression
Aggression


Atypical social behavior
Atypical social behavior

Poorly developed speech skills
Poorly developed speech skills

Avoids eye contact
Avoids eye contact

High-pitched or flat voice
High-pitched or flat voice

Difficulty with transitions
Difficulty with transitions

Repetitive behaviours
Repetitive behaviours


Slowed growth
Slowed growth

Abnormal hand movements
Abnormal hand movements

Breathing problems
Breathing problems

Seizures
Seizures

Problems in muscles coordination
Problems in muscles coordination

Irritation and Stress
Irritation and Stress


Regressive motor skills
Regressive motor skills

Poor bladder control
Poor bladder control

Restricted behaviours
Restricted behaviours

Lack of emotions
Lack of emotions

No social skills
No social skills

Lack of self-care
Lack of self-care


Limited facial expressions
Regressive motor skills

Difficulty sustaining friendships
Poor bowel/bladder control

Unusual sensitivity
Restricted behaviours

Obsessions
Lack of emotions

Hyperactivity
No social skills

Aggression
Lack of self-care

CAUSES
Studies have indicated that the cause of autism spectrum disorder has not been identified yet. In fact, researchers have pinpointed the combination of genetic, environmental factors responsible for the same.

CAUSES OF
AUTISM
  • Fetal presentation in the womb, multiple births, increased maternal age
  • Fetal distress, birth injury, hypoxia during birth, trauma along with neonatal anaemia
  • Multiple births increased maternal age and/or viral infection during gestation
  • Metabolic imbalance, immune dysfunction along with RH incompatibility
  • Rare maternal diseases like hyperbilirubinemia, liver dysfunction
  • Long term exposure to heavy metals & toxin exposure like mercury
  • Intrauterine exposure to viral infections like rubella, CMV and hepatitis
  • Genetic predisposition, epigenetic alterations and X-linked fragile syndrome
  • Other environmental factors like lifestyle changes, ageing during pregnancy
SUPPORTIVE THERAPY

“If it’s an autism, waiting for your child to catch on his own isn’t a solution; you need to act early to see a better version of your baby”

An increasing prevalence of neurodevelopmental issue has helped raise drastic awareness among parents. As it is very important for you to act early, if any of the symptoms or relative developmental issues are noted. Our rehabilitative programs for kids with autism are made to get maximum benefits. As per the guidelines published by the American Academy of Paediatrics (AAP), some of the proven therapies are:

Limited facial expressions
Occupational Therapy

Limited facial expressions
Occupational Therapy

Limited facial expressions
Occupational Therapy

Limited facial expressions
Occupational Therapy

Limited facial expressions
Occupational Therapy

Limited facial expressions
Occupational Therapy

Limited facial expressions
Occupational Therapy

Limited facial expressions
Occupational Therapy

OUTCOMES

Research has emphasized that adult stem cell therapy is absolutely safe form of treatment; although a lot of clinical development and refinement are on the way. The outcome obtained from clinical studies is remarkably positive and motivating. With rigorous data analysis, we propose a reversal and multimodal treatment showing clinical improvements in Autism through stem cell therapy.

Worldwide Clinical Studies using Stem Cells obtained from different sources

Improvement in clinical signs and symptoms
  • Showed improved eye contact with better response in following commands
  • Showed improved attention span
  • Expressed active involvement in communication and social interaction
  • Showed a significant reduction in behavioural issues like aggression, hyperactivity, stereotypical behaviour
  • Expressed more focused, sharp motor skills
  • Reported enhanced verbal skills
  • Reported improved emotional quotient
TESTIMONIAL

With the help of our comprehensive environment and advanced technologies, we believe in building trust and transparency with our patients. So far, we have provided stem cell therapy for Autism to a number of patients and their clinical improvements have been amazing. Check out some of our patient testimonials:

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Several studies are going on currently to assess the safety, efficacy, and feasibility of mesenchymal stem cells obtained from various sources like Umbilical Cord, Bone Marrow, and adipose Tissue. However, out of many types of MSCs enrolled for the study, umbilical cord-derived MSCs are proposed to be the best option for treating Multiple sclerosis, due to several obvious reasons

The cells are obtained from a very naïve source, the umbilical cord, and hence have faster self- renewal capacity as compared to other MSCs. These MSCs are pluripotent in nature as against the multipotent nature of MSCs obtained from other adult sources like Bone Marrow and Adipose Tissue. With a considerably higher dose e 1–2 × 106 cells/kg at 3-month intervals for 7 times, due to the higher expansion capacity of these cells, is quite cost-effective without much concern about safety and rejection.

FAQs

The diagnosis of MS is very challenging at an early stage because symptoms may be very non-specific and indicative of other diseases of the central nervous system. The early symptoms are very temporary causing no significant damage and hence are most of the times ignored easily by the people. Additionally, as such, no specific lab test is being used, apart from MRI; which can be significantly helpful in diagnosis. The complete diagnosis is always proportional to the expert based on the criteria.

In general, MS is not considered a fatal disease, but the quality of life can be significantly affected in patients suffering from Multiple Sclerosis. As such, there is no known full proof treatment available to reduce the sufferings. However, many therapeutic and technological advances are made in the field of stem cells to find a cure for the disease.

No, MS is not contagious neither it is directly inherited. Studies have indicated a mixed effect of both genes and environmental factors on the development of MS. Research has evidently suggested that susceptible individuals may have a familial genetic contribution for MS, however, these individuals need to encounter some triggering factor from the environment to actually develop MS. The research is still underway to pinpoint the exact location of the causative gene, its environmental cause, prevention and better treatment.

Yes, stem cells are the pristine cells of the body, which can give rise to many different types of cells upon proper signalling. These cells have been exploited successfully to differentiate into neurons. They have been isolated from the very own potent sources of our body known as Bone Marrow and Adipose Tissues. They can be minimally manipulated and implanted back into the body to promote neuroregeneration. They have also identified to be an effective guiding immune system to distinguish self-tissue from the non-self, thereby reducing further destruction.

Please go through, our treatment brochures for other Multiple Sclerosis related information.

 
Advancells is a strong advocate of greater transparency in medical procedures in general and Stem Cells Procedures in particular. As a part of our effort of bringing transparent procedures to our clients, we provide each client a Third Party Certificate (from an internationally accredited lab) for the cell count and viability of the cells that we are able to process from the autologous cell source of the patient. To view the sample copy of the certificate  click here

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