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Stem Cell Therapy for Parkinson's


Stem Cell Treatment For Parkinson

Parkinson's disease is the progressive disorder of the nervous system affecting movements. It develops gradually, starting with the barely noticeable tremors but in the later stage it is associated with frequent body stiffness and slowing or complete loss of movement.

People with Parkinsonism, like those with Parkinson’s disease, may experience muscular tremors (even in their relaxed phase), stiff muscles, delayed muscular movements and issues with locomotary actions, like balance, walking, etc.

Parkinson's disorder is a type of neurodegenerative disorder involving malfunctioning or death of vital nerve cells called neurons in the brain. The substantial cause of this neuronal degeneration is pinpointed as a decreased synthesis of dopamine hormone. This dopamine is involved in signal transmission process controlling and coordinating bodily movements. The progress of PD is associated with little or no production of dopamine, thus making a person unable to control muscular movements normally. Along with dopamine, clumps of proteins in brain cells are also said to be a prime suspect in Parkinson’s. They affect the non motor functions of the brain, such as sense of smell, sleep regulation etc.

With the new technology of stem cells, it is possible to proactively alter the effects of the disorders and live a full, happy, healthy life. Having the potential to significantly impact the development of diseased state these stem cells can create dopamine producing cells thus enhancing normal communication between neurons and providing a cure for a previously untreatable condition.


Major Manifestations of Parkinson's Disease, in patients include the following:

  • Tremor
  • Slowed movement
  • Rigid muscles
  • Loss of automatic movements
  • Speech changes

Parkinsonism, refers to the symptoms, similar to that if Parkinson’s disease but are caused due to another damaging brain disorders, like brain injury, viral encephalitis, poliomyelitis, Alzheimer’s disease, etc. The disorder, is mainly associated with neuronal blockage due to interfering action of a neurotransmitter; which, in turn affects the smooth muscular functions.

Although, symptoms are more or less similar to that of the Parkinson’s disorder; although some of them, which can distinguish other disorders from Parkinson's disease, may be noted as:

  • Prominent memory loss, during the first year of the disorder (May indicate dementia)
  • Symptoms of parkinsonism, only on one side of the body (Often due to certain brain tumors and/or corticobasal basal ganglionic degeneration.)
  • Low blood pressure, difficulty swallowing, constipation, etc.
  • Abnormal eye movements
  • Hallucinations as well as visual spatial problems
  • Inability to express and/or understand written, spoken languages, inability to do simple, skilled tasks, inability to associate objects with their usual roles, and/or function due to corticobasal ganglion degeneration.

Stem cells are believed to be natural transformers. Since conventional treatment options of Parkinson’s are asymptomatic with temporary effects, additionally the long term usage of steroidal drugs can further harm body with many side effects. In a variety of clinical trials and data, it has been evident that stem cells can naturally regenerate lost neurons, promote & regulate dopamine secretion. With the employment of adult autologous stem cells from your own bone marrow and adipose tissue, it is now possible to find out a permanent symptomatic solution for the same.

Stem cells are the mother cells of the body, mainly differentiating into the required types of cells upon channelizing through proper method. Research has evidently suggested that once inside the body, they can promote regeneration of lost neurons, regulate secretion of dopamine.The treatment reassures the safety of the patient.

The stem cell therapy approach mainly focuses on delivering the sufficient number of Adult Autologous Stem Cells which will travel into multiple areas of the damaged parts.

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Stem Cell Treatment

Stem Cell Treatment For Parkinson's Disease: Advancells Protocol

At Advancells we are exploiting the most potent stem cells isolated from patients own Bone Marrow or Adipose tissue or may be both depending upon the assessment. Our top priority is to provide very comprehensive, individualized treatment pattern which is best suited for the patients undergoing treatment.

Step 1- Qualification For The Treatment

A safety and efficacy assessments will be prescribed by our experts in order to investigate the stage of severity and qualify the patient for the treatment. Following pretreatment assessments can be suggested depending upon the patient’s medical and family background:

Pre-Treatment Assessments

  • Infectious disease testing
  • Physical Examination
  • MRI
  • CT-scan

As per these results, the patient will be counseled further for final decision of protocol.

Step 2- Source Extraction

With the physician’s approval and guidance, the source from which stem cells are to be collected is decided. In general patient can be prescribed, stem cells isolated from Bone Marrow or Adipose Tissue, as these are the most potent autologous sources available. However, in certain cases, both sources can be utilized for a better outcome. Doctors can also suggest stem cell stimulation therapy for some, depending upon the severity and requirement.

The specified amount of samples will be extracted from the patient’s own body on the intimated date and time, with the application of local anesthesia. The entire procedure takes around 7-8 hrs, however, in case of extracted from both the sources the patient has to be with us for a little longer time..

If you are curious to know more about the procedure, kindly refer our detailed snapshot below:

stem cell treatment for Parkinson

Step 3- Laboratory Processing

The extracted sample, will be sent to the government approved cGMP laboratory for processing. The sample processing will be done in a state of the art class 10,000 clean room in compliance with the ISO and GMP standards.

The sample will undergo minimum manipulation in our complete automated Sepax technology to be enriched with the pure population of stem cell culture. The isolated stem cells will be characterized for quality, purity and viability.

The client will be given a third party certificate from Internationally Accredited Lab for the quality purpose.

Step 4- Stem Cell Implantation

Once stem cells are enriched and ready to be injected back into the body, we have worked on different modes of implanting them. However, depending upon the patient’s physiological and mental well being, one of the following will be finalized by our experts.

Follow up Treatment

In a post treatment, care, the patient will be asked to visit the doctors after a specific period of time, for some rehabilitation programs, including assessment of tremors, physical behaviour, emotional behaviour.


Parkinson’s Treatment Results

Majority of the patients treated with us have shown marked improvement in overall control and coordination of the body, improved social and intellectual behavioural pattern.

Out of 75 patients who underwent Stem Cells Parkinson's treatment, 50% reverted with the clinical evaluation form. 36 patients reported of having significant clinical improvements. While the other patients failed to observe any changes.

Amongst them, 21 patients confirmed their improvements. 5 patients were able to lower their Parkinson’s related medication while 4 of them could even entirely stop the medication.

Majority of the patients reported a decline of motor parkinsonism (N=29), including rigidity and tremor. Results showed improved speech (N=24), dexterity (N=23), swallowing (N=20), handwriting (N=20), and stability (N=19). Thirty patients also reported of an increase in motivation and initiative. (Read more...)

Patient's Stories

Johannes Wolf - 72 years old

"...I no longer have any pain and I am completely drug free..."

Aubra Phillips - 59 years old

"...After the stem cell treatment for Parkinson's Cure, I would no longer freeze..."

Ted Ebertsch - 66 years old

"My neurologist saw me during this time and confirmed that I looked like I was doing very well..."

Jon Andresen - 71 years old

"Now, I am walking like I was before I had Parkinson's..."


Mr. B. Singh, Parkinson’s Treatment Video
Stem Cell Therapy Video for Parkinson's
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Frequently Asked Questions

  • What causes Parkinson’s Disease?
  • Parkinson’s is caused by progressive deterioration of neurons in the brain region known as Substantia Nigra. Neurons when signals normally they produce a kind of neurotransmitter known as Dopamine, which controls smooth and balanced muscular movement. A downregulation of dopamine may result in an abnormal nerve functioning leading to loss of ability controlling body movements.
  • What are the risk factors associated with the disease?
  • Although the root cause is still unknown, the disorder is mainly associated with the genetic abnormality.
  • What are the signs and symptoms of Parkinsons’ Disease?
  • Involuntary tremours, shaking voice, nodding head, tremours that worsen during emotional stress and lessen with rest, difficulty with balance, muscular rigidiy, changes in walking pattern and posture etc.
  • How is it conventionally treated & diagnosed?
  • Conventionally drug therapy and physical rehabilitation approach were applied as a treatment for parkinson’s, however the treatment did not prove to be effective in reversing the damage. Additionally, long term use of steroidal medicine could be very fatal, welcoming other unwanted side effects.
  • How can stem cells be beneficial to treat?
  • Undifferentiated adult autologous stem cells are mutable and can metamorph into countless number of cells as per the requirement. This remarkable property of stem cells can be exploited for treating a variety of diseases. These cells can be isolated from the most potent sources of our own body known as Adipose Tissue and Bone Marrow. Upon implanting back into the body, these cells can rapidly multiply with the great speed to restore damaged neurons, regularize the production of neurotransmitters including dopamine to retain the brain’s normal function back. In addition to stem cell therapy, a stimulation therapy can also be applied, wherein the organ is stimulated to multiply resident stem cells and secrete growth factors to create microenvironment. This treatment will act as a booster to promote regeneration.
  • Why is stem cells treatment better than conventional treatment approach?
  • Conventional treatment approach highly invasive associated with many side effects. Although stem cells can naturally heal the body from damage and regenerate lost neurons to improve impaired functions. Additionally, since body’s own cells are used for repairing, the entire treatment is minimally invasive without any side effects.
  • How do I know if I am the right candidate for the stem cells treatment?
  • There are many important issues to be addressed before opting for the treatment, which can satisfully answered only by experts. Thus, it is always advisable to consult, and opt for the right stem cells treatment pattern.
  • Where can I get more information about Disease?
  • Please go through, our treatment brochures for other Parkinson’s Disease related information.

What can you expect?

Many Parkinson's patients after stem cell treatment reported to be exhibiting

  • Improved control & coordination of the body
  • Improved social and intellectual behavior
  • Reduced pain
  • Improved self regulation
  • Improved Stamina and health fitness
  • Improved quality of life
  • Complete stoppage or progression of the disease