Stem cell Therapy for Spinal Cord Injury
With a unique approach combining Stem cells and Exosomes
Our Novel biologics address Unmet medical demands of many patients worldwide suffering from spinal cord injuries.
We are constantly upgrading our knowledge for the development of better therapeutics.
Stem Cell Treatment for Spinal Cord Injury
A devastating condition of the spinal cord due to sudden injury/trauma/accident, leading to loss of mobility, and sensation in different parts of the body. A spinal cord is packed with nerves relaying important messages from the brain to the rest of the body's organs. Sudden damage may halt the signals of the nerves causing a major functional loss in bladder/bowel movements, breathing, heart rate, sensation, reflexes, metabolism, and muscular movements. Conventionally, surgery and rehabilitative support were the only options to manage SCIs; however, recent studies are suggesting a holistic approach using neuroprotection, surgeries by repairing and regeneration, cell-based therapies, and retaining central nervous system circuits..
Stem Cell Therapy for Spinal Cord Injury: Advancells Protocol
Due to the ability of stem cells to differentiate into any cell type, their potential use in various cell- based therapeutic strategies makes more sense. The appropriate combination of surgeries, cell- based therapies, and retaining network-circuits long-term treatments could be achieved with various objectives like forming neurons and glial cells, functional recovery, and pain management. Exosomes offered along with mesenchymal stem cells are responsible for immune regulation post-stem cell therapy. This offers appropriate protection to the newly formed neurons, by serving as the first line of defense against injury-induced tissue loss, further contributing to the improved neurological outcome.
Procedure of Treatment of Spinal Cord Injury through Stem Cells Therapy
Treatment Qualification
Source Extraction
Processing of stem cells
Re-infusion
SPINAL CORD INJURIES
- Motor vehicle accidents are the leading cause of spinal cord injuries, accounting for almost 50% per year.
- After a certain age, specifically 65 and above, spinal cord injuries are often due to frequent falls.
- About 10-12% of spinal cord injuries are due to violent encounters, usually due to gunshot wounds during the war or knife wounds during fights.
- Certain chronic illnesses like cancer, arthritis, osteoporosis, and chronic inflammation can also cause damaged spinal cords.
- Horseback riding for a longer period can cause spinal cord injuries at certain levels.
- About 12% of spinal cord injuries occur during surgeries.
trigger points are activated to reduce the sense of pain and weakness. With the activation of these tense muscle nodules, there is a considerable reduction in pain as well as spasticity. It is also found to be important for improving gait speed and stability in patients with an incomplete form of injury.
As discussed previously, various studies have confirmed how a combination approach in the case of different types of spinal cord injury is helpful to offer holistic treatment right from posture control, and pain management to increased mobility and functional gain. Accordingly, on the basis of data collected from extensive studies to elucidate the mode of action of stem cells and exosomes infused in patients suffering from spinal cord injury; it can be suggested that
Majority of the patients treated at Advancells have shown marked improvement in bladder and bowel control function, improvement in muscle spasm and lesser neurogenic pain. Regenerative Therapy Innovations allow patients to get better control of their life and see improvements in their condition.
Find out how Stem Cell Therapy Is improving the lives of Spinal Cord Injury patients
TYPES OF SPINAL CORD INJURIES
CAUSES OF SPINAL CORD INJURIES
SPINAL CORD INJURIES
- Motor vehicle accidents are the leading cause of spinal cord injuries, accounting for almost 50% per year.
- After a certain age, specifically 65 and above, spinal cord injuries are often due to frequent falls.
- About 10-12% of spinal cord injuries are due to violent encounters, usually due to gunshot wounds during the war or knife wounds during fights.
- Certain chronic illnesses like cancer, arthritis, osteoporosis, and chronic inflammation can also cause damaged spinal cords.
- Horseback riding for a longer period can cause spinal cord injuries at certain levels
- About 12% of spinal cord injuries occur during surgeries.
SUPPORTIVE TREATMENT
Relevant studies have suggested further that the treatment of spinal cord injuries should always be multifaceted, considering the social and political context of the injuries. As stated earlier a combinational approach using surgeries, circuit devices for loss of sensation, and cell-based therapies along with exosomes can be helpful for significant improvement and symptomatic management of spinal cord injuries. Accordingly, we have come up with certain supportive treatments offered along with suitable treatment options, to promote neuroprotection, cellular repair as well as regeneration, and reduced inflammation.
OUTCOME
As discussed previously, various studies have confirmed how a combination approach in the case of different types of spinal cord injury is helpful to offer holistic treatment right from posture control, and pain management to increased mobility and functional gain. Accordingly, on the basis of data collected from extensive studies to elucidate the mode of action of stem cells and exosomes infused in patients suffering from spinal cord injury; it can be suggested that
TESTIMONIAL
Majority of the patients treated at Advancells have shown marked improvement in bladder and bowel control function, improvement in muscle spasm and lesser neurogenic pain. Regenerative Therapy Innovations allow patients to get better control of their life and see improvements in their condition.
Find out how Stem Cell Therapy Is improving the lives of Spinal Cord Injury patients
Must Read Articles on Spinal Cord Injuries
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Locking And Unlocking The Locked Knee
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Meta-analysis of Spinal Cord Injury using stem cell therapy
While the majority of the clinical trials on spinal cord injury patients were conducted using mesenchymal stem cells and exosomes; the results are variable from no improvements at all on the ASIA impairment scale to a recovery rate as high as 100%. Certain clinical investigations reported 100% safety and feasibility in the use of mesenchymal stem cells. On average almost 60% of the patients during the acute and sub-acute stages of spinal cord injury reported good improvement in motor functions, while 70% of them show some degree of neurological improvements like increased sitting tolerance, muscle strength, urine control, etc.
Better Body Regulation
Improved Sensory Function
Improvement in Circulatory System
Improvement in the Bladder Control
Improvement in the Bowel System
Reduced Inflammation in Injured Area
Restored Nerve Function
Recent Spinal Cord Injuries Patient Case Stories
Majority of the patients treated at Advancells have shown marked improvement in bladder and bowel control function, improvement in muscle spasm and lesser neurogenic pain. Regenerative Therapy Innovations allow patients to get better control of their life and see improvements in their condition.
Find out how Stem Cell Therapy Is improving the lives of Spinal Cord Injury patients
FAQs
Spinal Cord Injury is the result of a traumatic event causing damage to spinal cord or nerve tracts that relays signals from brain to other parts of body or body to brain. As a result, one could experience temporary or permanent loss of motor function, sensory function and autonomic function. According to the National Spinal Cord Injury Association, three classes of neural tissue damage leading to paralysis have been identified: Nerve cell death within the spinal cord Disruption of nerve pathways Demyelination, or destruction of the protective insulation surrounding axons, which conduct nerve signals
The most common causes of spinal cord injury are motor accidents, serious fall, acts of violence, sports injury and recreation accident, diseases such as spina bifida can also cause permanent injury to the spinal cord.
Paraplegia is a term used to describe the inability to move and sense the lower part of the body from the waist down, whereas the term tetraplegia or quadriplegia includes loss of motor and/or sensory function in the upper body, arms and hands.
The Central Nervous System is the most complex network of nerves in the body. Till date, even scientists are the mysteries of the brain and its network. However, the discovery of Stem Cells in modern science holds great promise in treating Spinal cord injuries. Stem Cell transplantation directly into the injured site leads to the generation of new nerve cells resulting in possible repair of axons and transmission of nerve signals. It has also been seen that Stem Cell transplantation given within few hours of Spinal Cord Injury can reduce the damage by releasing protective substances such as growth factors, and soaking up toxins such as free radicals, when introduced into the spinal cord shortly after injury and also preventing the spread of disease by reducing inflammation in the injured area.
Please go through, our treatment brochures for Spinal Cord Injury related information.
