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Stem Cell Therapy for Stroke

The Stem Cells-Exosome combined complex validates the saying that

A Comeback Should Always Be Stronger Than A Setback

A cutting-edge, therapeutic solution to offer post-stroke neuroprotection leading to improved functional outcomes.

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Stem Cell Treatment for Stroke

Stroke increases the susceptibility to neuronal damage leading to an overall loss in cognitive and motor functions. Following the acute phase of stroke, patients are currently recommended thrombolytic agents; nevertheless, many patients have enduring effects. While stem cell therapy post infusion can incorporate into the host brain and replace dead/damaged brain cells, reduce lesion size, and inhibit cell death suggesting an important role in cell-induced neuroprotection, immunomodulation, and downregulation of inflammatory responses.

Stem Cell Therapy For Stroke: Advancells Protocol

Several clinical trials are supporting the rationale use of stem cells isolated from some of the most potent available sources of mesenchymal stem cells. These trials are further supporting evidence that stem cell therapy, when combined with clot-busting and mechanical thrombectomy and infused through distant arteries or veins can travel to the site of a stroke to fuel repair processes.

Advancells is a research-oriented company working on exploiting panoramic applications of regenerative medicine using a variety of stem cells and exosomes isolated from them. Recent studies have indicated a prompt recovery in neurological processes. As per previous clinical investigations, the optimum time for introducing stem cells and exosome therapy seems to be between 36 hrs and 72 hrs after stroke.

The Procedure Of Treatment Of Stroke Through Stem Cell Therapy

Treatment Qualification

Source Extraction

Processing of stem cells

Re-infusion

STROKE THERAPY
STEM CELLS PROCEDURE
RESULTS
With a more in-depth understanding of various underlying mechanisms, on a broader aspect stroke can be classified into five different types, noted as:
Sudden numbness on the face, arm, and legs on one side of the body
Confusion
Problems speaking or understanding
Loss of balance, coordination
Visual loss
Trouble walking
Intense headache
Confusion
Frequent nausea or throwing up
Light sensitivity
Visual impairment
Passing out
Numbness or weakness on one side of the body
Confusion
Loss of balance
Trouble talking or understanding
Visual impairment
Severe headaches
Vertigo or dizziness
Double vision
Slurry speech
Frequent passing out
High blood pressure, heavy breathing
“Locked In” syndrome, can only move eyes
Irregular heartbeats
Unexplained chest discomfort
Lightheadedness
Fatigue
Shortness of breath
Extreme weakness on one side of the body
In the majority of reported stroke cases, obstruction of oxygenated blood supply to the brain is observed as the primary cause of stroke. Without oxygen in the blood, brain cells start dying leading to ischemia. In some other forms of stroke, like hemorrhagic stroke, brain cells die due to injury and bleeding in the brain. However, one should note that managing some of the controllable risk factors noted herewith can keep you away from a stroke. These risk factors include:
Causes-of-Stroke

CAUSES OF
STROKE
  • Consistently high cholesterol
  • Chronic high blood pressure
  • Previous history of heart disease
  • Long term smoking
  • Obesity
  • Metabolic syndrome
  • Sedentary lifestyle
  • Long-term excessive alcohol abuse
  • Sleep apnea
  • Thyroid disorders

Apart from the above-listed controllable risk factors, certain non-controllable risk factors are noted herewith. Early diagnosis and prompt treatment can prevent the risk of stroke.

  • Chronic dementia
  • Family history
  • Congenital heart defects
  • Congenital metabolic syndrome
  • Chronic diabetes mellitus
  • Chronic neurological illnesses
Your stroke treatment should begin immediately after being admitted to the emergency department; and should primarily be categorized into three parts, i.e. prevention of another stroke, definitive treatment to limit brain damage, and rehabilitation to treat the side effects of stroke.
Accordingly, we are suggesting a neurorehabilitation program that is carefully directed, well-focused and customized depending upon the skills that are lost or weakened during the process. On a general note, the suggested rehabilitation program includes:
Hyperbaric Oxygen Therapy Immediate administration of HBOT can improve the supply of oxygenated blood to the brain, further reducing brain swelling and protecting brain cells from damage. Regular sessions of HBOT can also help minimize sleep distress for a better outcome.
Accupuncture
AcupunctureWith the application of electric stimulation and pressure at specific trigger points, acupuncture post-stroke rehabilitation reported positive outcomes. Studies have indicated improved problems with pain, spasticity, and improved physical and cognitive functions.
PhysiotherapyPhysiotherapy has been very helpful for stroke survivors to relearn lost abilities, regain independence, and reduce the risk of further stroke. Studies have reported physiotherapy to be important for functional recovery and mobility after stroke.
Diet and NutritionA well-balanced diet supplemented with various beneficial nutraceuticals can support speedy recovery by boosting brain health. It is advisable to plan your diet with expert help, as some supplements can interfere with medications and worsen your health status.
Psychological counselingA lot of emotional and behavioral changes are reported in stroke survivors. However, the good news is that many disabilities and emotional turbulence tend to improve post-stroke with proper psychological counseling.
MT
Massage TherapyMassage therapy can help decrease paralysis/weakness of one side, improve sensation, increase coordination, decrease swelling and reduce stress.

Stem cell and exosome therapy hold tremendous promise to effectively improve damaged brain functions; because of their ability to differentiate into brain cells, reduce inflammatory cytokines and stimulate resident stem cells for a better paracrine response. As per previous studies, a lot of collected data supports speedy functional recovery in stroke survivors post stem cell therapy. They have further suggested:

Worldwide Clinical Studies using Stem Cells obtained from different sources

70% people have reported increased survival functions on an average with 87.76 months

With the administration of stem cells and exosomes, the primary goal is to offer speedy recovery, reduce the level of inflammation and regain functional attributes lost.

  • Paul Borgmann, 42 years, Stroke Patient

    Date of birth: 1964 Occupation: Programmer Marital status: Married, two sons (16 and 18) Disease treated: Stroke How it happened It happened in 2004 during the night when I was at home. I felt unwell, as I had been suffering from a weeklong headache. My wife called…

  • Ton, 63 years, Hemorrhagic Stroke

    Date of birth: 1943 Occupation: Municipal employee. Marital status: Married, two sons. Disease treated: Hemorrhagic stroke. How it happened It happened in April 2003. I was on my way into the dining room when I suddenly collapsed. Fortunately, my wife realised that I…

  • Patient story of Alvin Mueller, 84 years, Stroke

    Year of birth: 1923 Occupation: Retired Disease treated: stroke How it started “The feeling in my left arm and leg returned” At the age of 81, I suffered a stroke. The severe neurological damage caused the left side of my body, especially my left leg, arm but also my…

  • Preston Plevretes, 22 years, Stroke and severe brain injury

    Date of birth: 1986 Treatment date: 4-October-2007 Release date patient story: 25-November-2008 Treatment method: Lumbar puncture, muscle injections – Told by Preston’s mother Tammy Plevretes – Severe brain injury at a college football game Our son Preston was just…

  • Keith Buller, 57 years, Stroke Treatment Story

    Date of birth: 1951 Family: 4 children Occupation: Disabled, former exterminator Disease treated: Stroke Stroke following tooth infection A tooth infection got into my blood stream and developed into an endocarditis, which clogged my heart muscle and resulted in a…

  • Damla Uludag, 15 years, Stroke

    Home: Oss, Holland How It Happened On December 28, 2006, Damla experienced a cramp in her head and felt to the ground. When she tried to stand up again, she had no feelings in her left arm and leg. She fainted and an epileptic seizure followed. Damla stayed in the…

TYPES OF STROKE

Sudden numbness on the face, arm, and legs on one side of the body
Sudden numbness on the face, arm, and legs on one side of the body

Confusion
Confusion

Problems speaking or understanding
Problems speaking or understanding

Loss of balance, coordination
Loss of balance, coordination

Visual loss
Visual loss

Trouble walking
Trouble walking


Intense headache
Intense headache

Confusion
Confusion

Frequent nausea or throwing up
Frequent nausea or throwing up

Light sensitivity
Light sensitivity

Visual impairment
Visual impairment

Passing out
Passing out


Numbness or weakness on one side of the body
Numbness or weakness on one side of the body

Confusion
Confusion

Loss of balance
Loss of balance

Trouble talking or understanding
Trouble talking or understanding

Visual impairment
Visual impairment

Severe headaches
Severe headaches


Vertigo or dizziness
Vertigo or dizziness

Double vision
Double vision

Slurry speech
Slurry speech

Frequent passing out
Frequent passing out

High blood pressure, heavy breathing
High blood pressure, heavy breathing

Locked In syndrome, can only move eyes
“Locked In” syndrome, can only move eyes


Irregular heartbeats
Irregular heartbeats

Unexplained chest discomfort
Unexplained chest discomfort

Lightheadedness
Lightheadedness

Fatigue
Fatigue

Shortness of breath
Shortness of breath

Extreme weakness on one side of the body
Extreme weakness on one side of the body

CAUSES OF STROKE
In the majority of reported stroke cases, obstruction of oxygenated blood supply to the brain is observed as the primary cause of stroke. Without oxygen in the blood, brain cells start dying leading to ischemia. In some other forms of stroke, like hemorrhagic stroke, brain cells die due to injury and bleeding in the brain. However, one should note that managing some of the controllable risk factors noted herewith can keep you away from a stroke. These risk factors include:

Causes-of-Stroke

CAUSES OF
STROKE
  • Consistently high cholesterol
  • Chronic high blood pressure
  • Previous history of heart disease
  • Long term smoking
  • Obesity
  • Metabolic syndrome
  • Sedentary lifestyle
  • Long-term excessive alcohol abuse
  • Sleep apnea
  • Thyroid disorders

Apart from the above-listed controllable risk factors, certain non-controllable risk factors are noted herewith. Early diagnosis and prompt treatment can prevent the risk of stroke.

  • Chronic dementia
  • Family history
  • Congenital heart defects
  • Congenital metabolic syndrome
  • Chronic diabetes mellitus
  • Chronic neurological illnesses
SUPPORTIVE TREATMENT

Your stroke treatment should begin immediately after being admitted to the emergency department; and should primarily be categorized into three parts, i.e. prevention of another stroke, definitive treatment to limit brain damage, and rehabilitation to treat the side effects of stroke.
Accordingly, we are suggesting a neurorehabilitation program that is carefully directed, well-focused and customized depending upon the skills that are lost or weakened during the process. On a general note, the suggested rehabilitation program includes:

Hyperbaric Oxygen Therapy
Hyperbaric Oxygen Therapy

Acupuncture
Acupuncture

Physiotherapy
Physiotherapy

Diet and Nutrition
Diet and Nutrition

Psychological counseling
Psychological counseling

Massage Therapy
Massage Therapy

OUTCOMES

Stem cell and exosome therapy hold tremendous promise to effectively improve damaged brain functions; because of their ability to differentiate into brain cells, reduce inflammatory cytokines and stimulate resident stem cells for a better paracrine response. As per previous studies, a lot of collected data supports speedy functional recovery in stroke survivors post stem cell therapy. They have further suggested:

Worldwide Clinical Studies using Stem Cells obtained from different sources

70% people have reported increased survival functions on an average with 87.76 months
  • 70% of the survivors have shown improvements in locomotory functions/limb activities
  • 60% of the survivors regained abilities with thinking, attention, learning, judgment, and memory.
  • 60% of the survivors reported improved sensation, weakness, and reduced episodes of tremors.
  • 70% of the survivors have reported gaining good control over emotions and sleep.
  • 60% of the survivors have reported good control over the bladder and bowel.
TESTIMONIAL

With the administration of stem cells and exosomes, the primary goal is to offer speedy recovery, reduce the level of inflammation and regain functional attributes lost.

  • Paul Borgmann, 42 years, Stroke Patient

    Date of birth: 1964 Occupation: Programmer Marital status: Married, two sons (16 and 18) Disease treated: Stroke How it happened It happened in 2004 during the night when I was at home. I felt unwell, as I had been suffering from a weeklong headache. My wife called…

  • Ton, 63 years, Hemorrhagic Stroke

    Date of birth: 1943 Occupation: Municipal employee. Marital status: Married, two sons. Disease treated: Hemorrhagic stroke. How it happened It happened in April 2003. I was on my way into the dining room when I suddenly collapsed. Fortunately, my wife realised that I…

  • Patient story of Alvin Mueller, 84 years, Stroke

    Year of birth: 1923 Occupation: Retired Disease treated: stroke How it started “The feeling in my left arm and leg returned” At the age of 81, I suffered a stroke. The severe neurological damage caused the left side of my body, especially my left leg, arm but also my…

  • Preston Plevretes, 22 years, Stroke and severe brain injury

    Date of birth: 1986 Treatment date: 4-October-2007 Release date patient story: 25-November-2008 Treatment method: Lumbar puncture, muscle injections – Told by Preston’s mother Tammy Plevretes – Severe brain injury at a college football game Our son Preston was just…

  • Keith Buller, 57 years, Stroke Treatment Story

    Date of birth: 1951 Family: 4 children Occupation: Disabled, former exterminator Disease treated: Stroke Stroke following tooth infection A tooth infection got into my blood stream and developed into an endocarditis, which clogged my heart muscle and resulted in a…

  • Damla Uludag, 15 years, Stroke

    Home: Oss, Holland How It Happened On December 28, 2006, Damla experienced a cramp in her head and felt to the ground. When she tried to stand up again, she had no feelings in her left arm and leg. She fainted and an epileptic seizure followed. Damla stayed in the…

Must Read Articles on Regenerative Therapy for Stroke

Mesenchymal Stem Cell-Derived Exosome Therapy For Stroke
Mesenchymal Stem Cell-Derived Exosome Therapy For Stroke

Stroke, the leading cause of death and lifetime disability, devastating the lives of millions all around the world currently. Fortunately, for many of us stroke may seem to be bizarre, yet many of these stroke survivors have managed to get back on track quickly; well,...

Meta-analysis of treating stroke with stem cell therapy

The studies ongoing worldwide have reported that stem cell therapy can significantly improve neurological illnesses including stroke without severely noted adverse reactions. The results also suggested that stem cell therapy for stroke can be more effective if provided immediately after the incidence. The present meta-analysis was performed on 11 preclinical analyses, 18 independent interventions, and 11 clinical studies. The final reporting was done based on lesion volumes and modified neurological severity scores (mNSS) (Quian Ouyang et.al; 2019). For further information on stem cell therapy for stroke.

Please download the brochure

FAQs

Stem cells are the master cells of the body, which are able to differentiate into variety of cells if channelized properly. Stem cells isolated from autologous body sources such as Bone Marrow or Adipose Tissue are observed to be superior in vascularization i.e. formation of new blood vessels, clearing obstructed blood flow and regenerating dead cells. Various clinical trials have shown good improvements in patients.

Although, sooner is the better but depending upon the physical evaluations, doctors can tell you the best possible way through which you can avail this treatment.

During a stroke, a bystander should know the signs and act accordingly in time. If signs and symptoms of strokes are confirmed, like the person is losing an ability to speak, moving an arm or leg on one side or is experiencing facial paralysis on one side, then support him to avoid any physical injury. Ask someone to arrange for the ambulance as quickly as possible.

While hereditary factors play a role in the risk of stroke. There are many things, you can actually incorporate in your lifestyle to help reduce the risk of stroke such as avoiding smoking, excessive alcoholism, improved eating habits, regular exercises etc.

Please go through, our treatment brochures for other Stroke related information.

 
Advancells is a strong advocate of greater transparency in medical procedures in general and Stem Cells Procedures in particular. As a part of our effort of bringing transparent procedures to our clients, we provide each client a Third Party Certificate (from an internationally accredited lab) for the cell count and viability of the cells that we are able to process from the autologous cell source of the patient. To view the sample copy of the certificate  click here

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