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“Roughly 17.5% of the world’s population experience infertility in their lifetime”
-World Health Organisation

 

The longing for a child echoes through many hearts, because of the roadblocks on the path to fertility. Despite the hope brought by methods like In Vitro Fertilization (IVF), challenges persist for many. Fortunately, researchers are exploring a large number of ways, including stem cell therapy and surgeries. The former option, i.e., stem cell therapy, has revealed a new beacon of hope for couples looking to conceive.

In this blog, we will attempt to understand why stem cell therapy is more promising than established methods like IVF.

Stem Cell Therapy in Couple Fertility

Whenever we talk about couple infertility we believe that both the individuals of the couple need to be healthy to step into parenthood. But, statistics portray a different scenario. Approximately, 40% of infertility cases are related to males, 40% to females, and 20% to both sexes.

Several factors can induce infertility, including age factor, lifestyle factors, and sexually transmitted infections. It has been seen that 22% of married couples have difficulty conceiving compared to 13% of couples where women is younger than 30. Lifestyle changes like smoking, excessive alcohol use, and weight issues can all impact fertility. But the question comes, what can stem cell transplant do for couples facing infertility issues?

Stem cells are nano repair bots, which are the gift of nature to repair any damaged tissue.Stem cells are nano repair bots, which are the gift of nature to repair any damaged tissue. These cells possess the extraordinary ability to transform into various body tissue types. These cells then enter the body and can recognize the region where the damage has occurred to repair it. In certain cases, to get the best results we take the help of directly injecting the stem cells into the damaged site.

Let’s delve into the specific ways stem cell therapy offers hope for couples facing fertility challenges:

  1. Rejuvenating Sperm Production:

Male Infertility: There are many issues that can cause male infertility, including azoospermia and Oligospermia. Studies show that when mesenchymal stem cells are injected into the testicular tissue stimulates the growth of sperm-producing cells. This treatment helps men struggling with low sperm count or abnormalities by improving sperm quality and quantity. Even though these studies are still under significant research and ethical consideration they provide hope for a future where males struggling with infertility can be treated.

Erectile Dysfunction: Many men are experiencing erectile dysfunction in their early 20s as a result of their modern lifestyle. It is characterized by a high level of stress and a tendency toward sedentary behavior. As a result of the problematic nature of the condition itself, individuals seek treatment through a variety of methods, including implants, medications, and physical activity. However, it only helps to alleviate the symptoms; it does not involve treating the underlying cause of the condition. Stem cell treatment is a viable option that goes to the damaged tissue and helps repair the cause. 

  1. Addressing Ovarian Issues:

Premature ovarian failure (POF): Many women experience infertility due to POF because of diminishing egg reserves. Stem cell therapy offers a glimmer of hope as researchers are exploring the use of MSCs to stimulate the growth of primordial follicles (immature egg cells) in ovaries. In turn, researchers found that the MSCs can help stimulate ovulation and offer exciting possibilities for restoring ovarian function.

Endometriosis and scarring: The presence of endometriosis or scar tissue in the fallopian tubes can impede egg-sperm interaction and implantation. Researchers have found that MSCs injected into these areas demonstrate potential for reducing inflammation, promoting tissue repair, and improving the chances of successful fertilization of the eggs. MSCs also helps stimulate fast development of endometrial walls for successful implantation.

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IVF vs. Stem Cell Therapy: Weighing the Options

In Vitro Fertilization stands as the go-to option for assisted reproduction and the reasons include:

  1. High Success Rates: IVF boasts a robust track record of success. With consistent advancements in technology and medical expertise,  IVF has reliably provided solutions to infertility challenges. 
  2. Established Guidelines: IVF has received considerable ethical considerations, where medical institutes and governments have guidelines in place. 
  3. Address Various Infertility Causes: One of the strengths of IVF lies in its versatility. If couples are facing a myriad of challenges, IVF can help them step into parenthood. 
  4. Overcoming Age-Related Challenges: Age is another reason why couples are facing infertility issues. Couples have taken the help of donor eggs and sperm to have a baby in the later stages of life, where normal conception is perceived to be difficult.IVF vs. Stem Cell Therapy: Weighing the Options

As we pointed out earlier, stem cell transplantation can target the underlying cause of infertility. Additionally, Stem cell therapy has several advantages over established assisted reproduction, including

  1. Personalized Treatment: Stem cell therapy takes the personalized route that helps couples address specific fertility challenges. The treatment can be tailored and can target the root cause of infertility.
  2. Regenerative Potential: Unlike IVF, Stem cell treatment targets the underlying mechanism. It helps repair the damaged tissue either by repairing or regenerating the tissue, The treatment provides a holistic solution to the couples, potentially surpassing the limitation of the existing methods.
  3. Ongoing Research: The field of stem cell therapy is under constant research and is now undergoing clinical trials at various stages. There are studies that have shown promise in treating infertility in males and females with varying success rates. The success rates to treat male infertility weighs on the heavy side but it gives hope to couples to step into parenthood. 

Embarking on the journey of parenthood demands informed decisions. One must carefully weigh all the pros and cons of the treatment they choose to bring a baby into the world.

Stem Cell Therapy Success Stories 

1) Mr. L.N.’s Treatment for Erectile Dysfunction

Mr. L.N. aged 34 was facing despair after experiencing erectile dysfunction. While trying to find a cure for his condition, his online research led him to stem cell therapy that offered a glimmer of hope. After thorough consultations and evaluations, he decided to undergo a procedure using umbilical cord-derived mesenchymal stem cells. Post three months of treatment, 

Mr. L.N. saw that he was able to regain morning erections and experienced a 70% increase in erection quality.  In his own words:

“Yes, I have experienced marvelous improvement in my condition. And the effects of treatment have met my expectations.”

This steady progress continues, exceeding his expectations. Stem cell therapy wasn’t just a treatment; it was a life-changer.

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2) Anita Sharma’s Becomes a Mother

At the age of 26, Anita’s dream of motherhood felt tragically distant. She was suffering from irregular and painful, and multiple miscarriages were making her lose hope of becoming a mother.  Even IVF, could not help her foster a child and ended in repeated failed pregnancy. 

She then came across a new treatment option called stem cell therapy for treating her condition. Upon diagnosis, doctors told her that she suffered from an endometrial thinning condition, which made it difficult for her to get pregnant. A condition that has shown promise in clinical trials. She decided to undergo therapy for the treatment. She underwent the treatment and as a surprise to the medical team and Anita, four weeks post-treatment she was able to get a positive pregnancy test. She went ahead with the pregnancy and gave birth to a baby girl.

“…I got to know that I am pregnant! It was the happiest day of my life!”

This isn’t just a success story; it’s a beacon for women facing similar challenges.

Conclusion

While IVF remains a reliable solution for many, stem cell therapy emerges as a promising contender with exciting potential. Its personalized approach, ability to target specific issues, and ongoing research paint a hopeful picture for couples battling infertility. However, informed decisions call for weighing both options carefully, considering success rates, established guidelines, and personal needs. Remember, the journey to parenthood is unique, and the answer lies in choosing the path that best illuminates your way.

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