Male Infertility Protocol

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    Stem Cell Treatment For Male Infertility: Advancells Protocol

    Treatment at Advancells involves use of adult stem cells from patients very own body as a tool for repairing ED. We at Advancells are exploiting the most potent stem cells isolated from patients own Bone Marrow or Adipose Tissue or maybe both depending upon the assessment. Our top priority is to provide very comprehensive, individualized treatment pattern which is best suited for the patients undergoing treatment.

    The patients suffering from erectile dysfunction are mainly treated by injecting the stem cells into the penile artery via catheter. Patients also have the option of getting the stem cell infused into the blood flow through the process of intravenous injection.

    Step 1- Qualification For The Therapy

    A safety and efficacy assessments will be prescribed by our experts in order to investigate the stage of severity and qualify the patient for the treatment. Following pretreatment assessments can be suggested depending upon the patient’s medical and family background:

    Pre-Treatment Assessments

    • Routine Blood Tests
    • Infectious Disease Testing
    • Urine Analysis
    • Physical Examination
    • Ultrasound
    • Overnight erection test

    As per these results, the patient will be counseled further for final decision of protocol.

    Step 2- Source Extraction

    With the physician’s approval and guidance, the source from which stem cells are to be collected is decided. In general patient can be prescribed, stem cells isolated from Bone Marrow or Adipose Tissue, as these are the most potent Autologous sources available. However, in certain cases, both sources can be utilized for a better outcome. Doctors can also suggest stem cell stimulation therapy for some, depending upon the severity and requirement.

    The specified amount of samples will be extracted from the patient’s own body on the intimated date and time, with the application of local anesthesia. The entire procedure takes around 7-8 hours. However, in case of extraction from multiple sources the patient might need to stay for a little longer time.

    If you are curious to know more about the procedure, kindly refer the detailed info graphic below:

    Step 3- Laboratory Processing

    The extracted sample, will be sent to the government approved cGMP laboratory for processing. The sample processing will be done in a state of the art class 10,000 clean room in compliance with the ISO and GMP standards.

    The sample will undergo minimum manipulation in our complete automated Sepax technology to be enriched with the pure population of stem cell culture. The isolated stem cells will be characterized for quality, purity and viability.

    The client will be given a third party certificate from Internationally Accredited Lab for the quality purpose.

    Step 4- Stem Cell Implantation

    Studies have shown that male germ cells have been successfully derived though trans differentiation from bone marrow/adipose derived stem cells.

    Stem Cell Dose: Stem cells containing 50 million cells in 3-5 ml will be prepared and injected into testis.

    Stem cells will be injected intra-testicularly and intravenously. Intra testicular injection consisted of bilateral testicular stem cell infiltration/injection. An ultrasound of the testes will be done after the procedure to ensure good depth of stem cell injection.

    Follow up Treatment

    Gonadotrophin therapy is started daily 75 IU HMG followed by 75 IU of FSH for three months.

    After 12 weeks Serum Hormonal Profile:(elevation of testosterone levels, decrease in FSH, LH and Prolactin Levels); Testicular Size (increased size); and Sexual Potency (increased sexual potency) will be assessed. A testicular biopsy will be done 3 months later. 


    “Advancells is a strong advocate of greater transparency in medical procedures in general and Stem Cells Procedures in particular. As a part of our effort of bringing transparent procedures to our clients, we provide each client a Third Party Certificate (from an internationally accredited lab) for the cell count and viability of the cells that we are able to process from the autologous cell source of the patient. To view the sample copy of the certificate  “click here



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