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Stem Cell Therapy For Female Infertility

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Stem Cell Therapy For Female Infertility

With increasing complications in the female reproductive system, due to major lifestyle alterations like PCOD, poor ovarian reserves, endometrial thinning etc.; conventional medicine fails to produce desired therapeutic outcome. These shortcomings can be overcome by exploiting the exemplary ability of stem cells and exosome cocktail; which has already been proven in various clinical studies. With our combinational approach, using stem cells, exosomes and p-shots; we have observed major improvements in women with fertility issues.

Some Common Problems in Female Infertility

Asherman Syndrome
Asherman’s syndrome is an acquired disorder of the uterus, characterized by unusual scarring of the walls of the uterus; which can further decrease the volume of the uterine cavity. This scarring can be a result of surgical scraping, uterine curettage, as well as endometrial infection. The indication can be mild to severe causing a varying degree of discomforts, such as urinary incontinence, abdominal cramping, pelvic pain, and eventual stoppage of the menstrual cycle leading to infertility. While conventional medicine is offering only restorative techniques, the latest technology like stem cells and exosome combination along with p-shot is found to be very effective in regeneration of the uterine wall, resumption of menstruation, and increase in the chances of fertility.
Endometrial Thinning
The clinical success of pregnancy largely depends upon the ability of the endometrium to implant fertilized embryo and nurture it for its development. However, sufficient data is collected further stating that severe malfunctioning of resident progenitor cells, due to a variety of reasons can lead to early endometrial thinning that may further fail to implant the developing embryo. The current conventional treatments available for endometrial thinning is very time-consuming with varied degree of success s rates. While stem cell therapy has been proven to be advantageous in multiple ways.
Primary Ovarian Insufficiency
Primary ovarian insufficiency is a reproductive disorder characterized by less or no production of ova. While conventional therapies are mostly relying on restorative actions along with assisted reproductive techniques to overcome issues of poor ovarian reserves, the failure rate is high. At the same time, studies have raised particular interest in providing the right environment for the development and production of the oocyte from primordial follicles; which can be accomplished through adult stem cell therapy. We have come up with the combinational approach to provide adult stem cells along with exosomes and your autologous P-shot for the creation of an apt micro-environment to product oocytes.

Stem Cell Therapy For Female Infertility: Advancells Protocol

In recent years, researchers have diverted their attention toward treatment possibilities of regenerative medicine; and promoted it as a mainline treatment. Various studies have pinpointed the potential of mesenchymal stem cells and stem cell-derived exosomes to regulate pathophysiological mechanisms associated with ovarian aging and endometrial thinning, further reporting several live births. As per the data, Advancells is successful in bringing forth a promising combinational approach using mesenchymal stem cells along with exosomes and autologous P-shots to treat the number of female fertility issues, listed herewith.

Stem Cell Therapy for Female Infertility at Advancells is divided into 4 steps

Qualification For The Treatment
Source Extraction
Laboratory Processing
Implantation
STEM CELLS THERAPY
STEM CELLS PROCEDURE
RESULTS
Intense research has explored various complex mechanisms between mesenchymal stem cells, their internal communication, and the pathophysiology associated with female infertility. A more rigorous approach is required for clinical application. Various types of female infertility issues for which the safety and efficacy of stem cell therapy have been established are as follows:
Pelvic pain
Pelvic pain
Pain during intercourse
Pain during intercourse
Painful bowel movements or urination
Painful bowel movements or urination
Excessive, untimely bleeding
Excessive, untimely bleeding
Back pain
Back pain
Diarrhea, nausea
Diarrhea, nausea
Frequent mood changes, irritability
Frequent mood changes, irritability
Unusual fatigue
Unusual fatigue
Acne
Acne
Excessive body hair growth
Sudden weight changes
Irregular periods
Irregular periods
Blood in the urine
Pain during urination, bowel movements
Skin rashes
Dental Decay
Joint pain
Joint pain
Fatigue
Fatigue
Too low body weight
Too low body weight
Depression
Depression
Low sex drive
Low sex drive
Thyroid dysfunction
Thyroid dysfunction
Irregular periods
Inability to conceive
Unusually heavy bleeding during menstruation
Unusually heavy bleeding during menstruation
Pelvic pain
Pelvic pain
Constipation
Bloating
Bloating
Anemia
Frequent need for urination
Frequent need for urination
Infertility is a complex disorder with significant social, economic, financial, genetic aspects. The most identifiable female factors accounting for 80% of the female infertility are found to be ovulatory disorders and endometriosis
  • Problems with the uterus, leading to the development of fibroids, polyps, septum, etc.
  • Chronic pelvic inflammatory diseases are usually caused due to bacterial infection
  • Hormonal imbalance leading to poor ovarian reserves, polycystic ovarian syndrome
  • Long term use of steroid medications or birth contraceptives
  • Endometrial cancer
  • Other disorders of the endocrine system lead to hormonal imbalances
  • Intrauterine exposure to viral and/or bacterial infection
  • Other environmental factors include stress, depression, etc.
  • Increased maternal age

“The science of stem cell therapy is hope for female infertility issues, against all odds and all logic! ”

To get maximum benefits of stem cells and exosome therapy it is always better to act early. Experts are also emphasizing adding many supportive therapies as a part of a therapeutic alliance for maximum clinical benefits. Some of the supportive rehabilitation therapies have proven to be effective in offering great benefits for your body as well as your mind.
Hyperbaric Oxygen Therapy Hyperbaric oxygen sessions offered post stem cell therapy are identified to be extremely beneficial in minimizing oxidative stress, improving vasculogenesis, and reducing inflammation. In women, it is also proven to help stimulate oogenesis, decrease inflammation in endometriosis, and in improving the quality of eggs.
Regular Exercise/AerobicsWomen are advised to keep up their regular exercise routine to combat issues associated with fertility. Regular exercise may help them to maintain their stamina, and heartbeat and improve lung efficiency for a higher degree of oxygen saturation.
AcupunctureRecently, acupuncture has been accepted as an auxiliary method to increase fertility. Various studies have confirmed that acupuncture can stimulate neuronal functions, hypothalamic functions, and ovarian functions. Acupuncture also helps to effectively activate signaling pathways to regulate inflammatory processes. Some studies have also reported that acupuncture can help in the production of gonadotropin, which in turn is responsible for the selection of dominant follicles that are required for embryo implantation.
Hydrotherapy Recently hydrotherapy i.e., physical training or working out in water is gaining good popularity due to its outstanding results. As confirmed in traditional literature, water has great healing power. It can help decrease your muscle tension, align your body structure and systems, effective pain management, fight depression, and reduce various female reproductive health organ issues.
Herbal medicationsEndocrine imbalance is identified to be the preliminary reason for fertility-related complications; for which oral administration of herbal medicine has had an obvious impact. An herbal diet is suggested based on the fertility score to help build immune strength and visceral strength.
Psychological The therapy is specifically designed to enhance processing skills of sensory information; such as textures, sounds, smell, taste, brightness etc. With the rationale of understanding how information is being processed in their brain, children are helped to make better sense of information that can be used in doing multiple tasks on a daily basis.
Dietary ModificationFor some children with autism, certain dietary changes have reportedly produced dramatic differences in the symptomatic exhibition and functional improvements. With good scientific investigation, experts believe that children with autism are to be evaluated for certain dietary modifications, either in combination or alone; in order to evaluate significant functional improvement in the brain.
Psychological InterventionsIt aims at shaping behavioural issues using classic and/or instrumental conditioning. It is designed with objectives to focus mainly on core deficits associated with mental issues or psychological challenges reported in the spectrum.

Stem cells hold promise for the treatment of female infertility because they can regenerate and develop into many cell types. According to mounting data from pre-clinical and clinical trials, stem cells may be capable of restoring menstruation, and hormonal levels, and have the power to treat female infertility. Some of the improvements in female reproductive dysfunction include:

Worldwide Clinical Studies using Stem Cells obtained from different sources

70% people have reported increased survival functions on an average with 87.76 months

We have successfully used stem cells to treat patients with female infertility issues. Our primary goal is to consistently provide thorough, individualised regenerative therapy that is most suitable for patients receiving stem cell therapy.

  • Anita Sharma, 33 years old, Female Infertility Patient Story

    Anita Sharma, 33 years old, India Name: Anita Sharma Age: 33 years old Condition: Endometrial Thinning, Multiple Miscarriages Failed Pregnancies I was diagnosed with endometrial thinning at the age of 26 years. My periods were painful and irregular most of the time. I…

FEMALE INFERTILITY TYPES

Pelvic pain
Pelvic pain

Pain during intercourse
Pain during intercourse

Painful bowel movements or urination
Painful bowel movements or urination

Excessive, untimely bleeding
Excessive, untimely bleeding

Back pain
Back pain

Diarrhea, nausea
Diarrhea, nausea


Frequent mood changes, irritability
Frequent mood changes, irritability

Unusual fatigue
Unusual fatigue

Acne
Acne

Excessive body hair growth
Excessive body hair growth

Sudden weight changes
Sudden weight changes

Irregular periods
Irregular periods


Blood in the urine
Blood in the urine

Pain during urination, bowel movements
Pain during urination, bowel movements

Skin rashes
Skin rashes

Dental Decay
Dental Decay

Joint pain
Joint pain

Fatigue
Fatigue


Too low body weight
Too low body weight

Depression
Depression

Low sex drive
Low sex drive

Thyroid dysfunction
Thyroid dysfunction

Irregular periods
Irregular periods

Inability to conceive
Inability to conceive


Unusually heavy bleeding during menstruation
Unusually heavy bleeding during menstruation

Pelvic pain
Pelvic pain

Constipation
Constipation

Bloating
Bloating

Anemia
Anemia

Aggression
Frequent need for urination

FEMALE INFERTILITY CAUSES
Infertility is a complex disorder with significant social, economic, financial, genetic aspects. The most identifiable female factors accounting for 80% of the female infertility are found to be ovulatory disorders and endometriosis

  • Problems with the uterus, leading to the development of fibroids, polyps, septum, etc.
  • Chronic pelvic inflammatory diseases are usually caused due to bacterial infection
  • Hormonal imbalance leading to poor ovarian reserves, polycystic ovarian syndrome
  • Long term use of steroid medications or birth contraceptives
  • Endometrial cancer
  • Other disorders of the endocrine system lead to hormonal imbalances
  • Intrauterine exposure to viral and/or bacterial infection
  • Other environmental factors include stress, depression, etc.
  • Increased maternal age
SUPPORTIVE THERAPY

“The science of stem cell therapy is hope for female infertility issues, against all odds and all logic!”

To get maximum benefits of stem cells and exosome therapy it is always better to act early. Experts are also emphasizing adding many supportive therapies as a part of a therapeutic alliance for maximum clinical benefits. Some of the supportive rehabilitation therapies have proven to be effective in offering great benefits for your body as well as your mind.

Hyperbaric Oxygen Therapy
Hyperbaric Oxygen Therapy

Regular Exercise/Aerobics
Regular Exercise/Aerobics

Acupuncture
Acupuncture

Hydrotherapy
Hydrotherapy

Herbal medications
Herbal medications

Psychological
Psychological

Dietary Modification
Dietary Modification

Psychological Interventions
Psychological Interventions

OUTCOMES

Research has emphasized that adult stem cell therapy is absolutely safe form of treatment; although a lot of clinical development and refinement are on the way. The outcome obtained from clinical studies is remarkably positive and motivating. With rigorous data analysis, we propose a reversal and multimodal treatment showing clinical improvements in Autism through stem cell therapy.

Worldwide Clinical Studies using Stem Cells obtained from different sources

Improvement in clinical signs and symptoms
  • Showed improved eye contact with better response in following commands
  • Showed improved attention span
  • Expressed active involvement in communication and social interaction
  • Showed a significant reduction in behavioural issues like aggression, hyperactivity, stereotypical behaviour
  • Expressed more focused, sharp motor skills
  • Reported enhanced verbal skills
  • Reported improved emotional quotient
TESTIMONIAL

We have successfully used stem cells to treat patients with female infertility issues. Our primary goal is to consistently provide thorough, individualised regenerative therapy that is most suitable for patients receiving stem cell therapy.

  • Anita Sharma, 33 years old, Female Infertility Patient Story

    Anita Sharma, 33 years old, India Name: Anita Sharma Age: 33 years old Condition: Endometrial Thinning, Multiple Miscarriages Failed Pregnancies I was diagnosed with endometrial thinning at the age of 26 years. My periods were painful and irregular most of the time. I…

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FAQs

In general, terms, if you have been unable to conceive in the normal way, even after a reasonable period; it is advised to seek medical help for effective evaluation and treatment of female infertility. Some of the general fertility tests suggested are:

  • Ovulation testing: The at-home ovulation predictor kits are helpful to confirm the ovulation period through the detection of a surge in luteinizing hormones (LH). Apart from the same, other important hormones like progesterone, prolactin, etc. can be checked to confirm the status.
  • Hysterosalpingography: During this procedure, a uterine X-ray is taken to assess structural defects of the uterus like fallopian tube leakage, uterine thinning, etc.
  • The ovarian reserves testing: It is helpful to assess the quality and quantity of eggs available for ovulation.
  • Imaging analysis: Sonography imaging is used to see details inside the uterus and assess whether any structural abnormality is present.

Besides conventional medical treatments for female infertility like in vitro fertilization, surrogacy, etc. science and technology have advanced in the field of regenerative medicine as well. Studies have indicated that with the help of a combinational approach like stem cells and autologous platelet-rich plasma, it is possible to address various issues contributing to female infertility like endometriosis, uterine thinning, poor ovarian reserves, etc. Stem cells can potentially differentiate into cells of uterine origin, as they are the naïve cells formed during fetal development and can be differentiated into various other cell types except for cells of the placenta. The autologous platelet-rich plasma can be helpful to regulate inflammatory markers in the body to reduce inflammation and the aging process.

If you think that you and your partner may need to seek medical help for getting pregnant, here is what you can do:

  • Talk to your healthcare practitioners: you can seek general advice from your healthcare practitioners and ask for their opinion. You can also request him/her to suggest a fertility specialist.
  • Discuss your family health history: With fertility experts, you can discuss issues about your family history, prior history of miscarriages, conceptions, lifestyle, diet, etc.

Various case studies have reported multiple health issues post applications of assisted reproductive technologies. Some of the commonly reported health problems are

  • Ovarian hyperstimulation syndrome (OHSS)
  • An increased incidence of multiple pregnancies
  • An increased risk of premature labor and low birth weight
  • An increased risk of delivery through c-section

 
Advancells is a strong advocate of greater transparency in medical procedures in general and Stem Cells Procedures in particular. As a part of our effort of bringing transparent procedures to our clients, we provide each client a Third Party Certificate (from an internationally accredited lab) for the cell count and viability of the cells that we are able to process from the autologous cell source of the patient. To view the sample copy of the certificate  click here

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