Treatment of Female Fertility
Treatment of Female Infertility with Stem Cells
Strategies to overcome infertility with stem cells target the reasons of infertility based on femaleinfertility diagnosis of poor ovarian reserve, Asherman syndrome, and endometrium thinning after assessment of infertility symptoms. Nowadays, many couples in developed countries are facing issues in treatment of female infertility.Earlier the issues leading to female infertility diagnosis were not clearly known but with extensive research, scientists are exploiting new treatments of female infertility using autologous transplant/allogenic transplant for adipose-derived mesenchymal stromal cells treatment and bone marrow stromal cells treatment. This new insight on treatment of female infertility has helped in identifying the potential to overcome infertility with stem cells, primarily using autologous stem cell transplant in form of hematopoietic stem cell transplant or mesenchymal stromal cells treatment.
Some Common Problems in Female Infertility
Asherman Syndrome
Asherman’s syndrome (intrauterine adhesions) is an acquired condition, characterized with the fibrous scarring inside the uterine cavity. These adhesions can result in the obstruction of intrauterine cavities and cervical canal. Some of the commonly noted symptoms of Asherman’s syndrome are reduced menstrual flow, pelvic pain, and infertility.
Incidence: In infertile female populations the prevalence of Asherman’s syndrome varies from 2.8% to 46%.
Endometrial Thinning
The preparation of the endometrium tissue for receiving embryo is associated with a period of hyperproliferation and angiogenesis in the uterus. The endometrial thickness expands by 5–7 mm in each menstrual cycle and a great amount of tissue remodeling, growth factor secretion, and endothelial sprouting occur in a tightly regulated manner. Endometrial thinning in the uterus is considered as a critical factor in embryo implantation failure and pregnancy rates have been reported to decrease in case of inadequate endometrial thickness.
Incidence: For endometrial thinning, an incidence of 5% has been reported in women <40 years and 25% for >40 years.
Poor Ovarian Reserve
Poor ovarian reserve condition in females is heavily influenced by the lack of both quality and quantity of oocytes. This is fueled by ovarian aging, which results in ovarian fibrosis and complete ovarian failure in severe cases, leading to the loss of fecundity.
Incidence: In general, the incidence of poor ovarian reserve response ranges from 10 to 20%.
Best Treatment for Infertility with Stem Cells: Advancells Protocol
Stem Cell Therapy for Female Infertility at Advancells is divided into 4 steps
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FAQs
Advancells is a strong advocate of greater transparency in medical procedures in general and Stem Cells Procedures in particular. As a part of our effort of bringing transparent procedures to our clients, we provide each client a Third Party Certificate (from an internationally accredited lab) for the cell count and viability of the cells that we are able to process from the autologous cell source of the patient. To view the sample copy of the certificate click here
