Stem Cell Therapy For Liver Damage

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With our comprehensive approach offering stem cells and stem cell-derived exosomes,
it is much easier for people with a damaged liver to manage disease progression.

Stem Cell Treatment for Liver Disorders

In the past 50 years, there has been a considerable increase in the incidence and mortality of liver disorders. Along with the same, incidences of associated complications depending upon the severity of the disorders have also risen significantly. Although the liver is the only organ with a natural capacity for regeneration, there is still a large gap between regeneration and liver damage. Thus, the increasing prevalence of liver disorders questions the only available proven treatment, the liver transplant; and demands an alternative therapeutic solution.

Stem cell Therapy for Liver Disorders: Advancells Protocol

The years of research pertaining to regenerative medicine, including cellular therapies have confirmed the potential use of combination therapies including mesenchymal stem cells and exosomes to treat multiple liver ailments. There are currently around 16 clinical trials going on using mesenchymal stem cells worldwide, and all of them have confessed that MSCs would be the ideal candidates for treating liver diseases by managing both tissue damage and the overactivation of inflammation.

Procedure of Treatment of Liver Damage through Stem Cells Therapy

Treatment Qualification

Source Extraction

Processing of stem cells

Re-infusion

With high mortality and morbidity, different types of liver diseases play a major threat currently across the globe. Due to various stimuli like drug abuse, viral infection, diet changes, vaccinations as well as and autoimmune attacks; the medical fraternity has reported an increasing prevalence of liver ailments. Liver disorders can be categorized into different types:
Fever
Fatigue
Loss of appetite
Nausea
Vomiting
Abdominal pain
Abdominal swelling
Visibly enlarged blood vessels beneath the skin surface
Red palms
Yellowing of the skin and eyes
Enlarged spleen
Excessive fatigue
Excessive fatigue
Weight loss
High blood pressure
Confusion or drowsiness
Passing blood through stool
Swelling in the ankles and tummy
Itchy skin
Yellowing of the skin
Vomiting blood
Bleeding and/or bruising continuously
Loss of sex drive
Swollen legs or tummy from a build-up of fluid
Fatigue
Abdominal symptoms
Abnormal blood vessels on the skin
Skin rashes
Loss of menstrual blood
An enlarged liver
Studies have indicated that the

Liver damage can be life-threatening, if not attended immediately. Most often liver damage is a gradual process, happening due to liver abuse over a period of time. However, there are certain acute conditions caused due to multiple cases of abuse.

Accordingly, certain causes of liver disorders include:

CAUSES OF
LIVER DISORDERS
  • Viral pathogenic infections causing inflammation
  • Long-term alcohol consumption leading to liver cirrhosis
  • Long-term consumption of oily, fatty food leading to liver damage and inflammation
  • Eating poisonous wild mushrooms.
  • Autoimmune attack on the liver, leading to inflammatory damage of the virus
  • Acute fatty liver during pregnancy, causing excessive deposition of fat on the liver
  • Certain other overwhelming infections in the body can cause progressive liver damage
  • Drug overdose, including acetaminophen can damage liver function leading to progressive liver disorders.
  • Due to a rare genetic disorder named Wilson’s disease; the body’s copper-removing capacity is hampered leading to the deposition of copper in the liver causing its progressive damage.
Many studies have confirmed the application of various supportive treatments to aid in the therapeutic benefit of liver disorders. Apart from cell-based therapies using a combinational approach of stem cells and exosomes, it is possible to reduce liver inflammation due to external abuse; promoting its functional regeneration. Moreover, the liver is the body’s only organ with self- regeneration capacity due to the presence of residual liver stem cells and hepatocyte progenitor cells. Accordingly, the holistic approach offering effective rehabilitation therapies can speed up its regeneration capacity.
Hyperbaric Oxygen Therapy Hyperbaric oxygen therapy is observed to be effective in reducing inflammation in the body, further supporting the regulation of aging factors. This may lead to functional restoration of the liver.
PhysiotherapyStudies have confirmed that regular exercise can improve skeletal muscle mass, strength, and overall functional endurance. It also supports improvement in cardiopulmonary functions and digestion of lipids. Thus, regular exercise is suggested to improve digestion and reduce stress on the liver.
Speech TherapyIt addresses challenges with language and communication. It helps children with autism to improve verbal, non-verbal and social communication. The goal is to help children improve communication skills in more functional ways.
Diet/NutritionExperts have suggested that dietary management is very important in patients suffering from liver disorders. As a recommended guideline, the recommended energy intake in case of liver disorder should be between 35-40 kcal/kg/day. A more fibrous diet can be easily digested putting less pressure on the liver for easy digestion.
Psychological counselingPsychological counseling is suggested to tackle multiple issues like mood swings, stress eating, depression, fatigue, etc. A good diet, regular exercise, and psychological well-being are identified to be very effective in overall well-being.

As discussed previously, various studies have confirmed how a combination approach using stem cell therapy and exosomes is highly effective in minimizing inflammation and regularizing immune factors to support the functional restoration of the liver. Accordingly, the assessments done on the basis of extensive data collected from a large number of clinical investigations have proven that

Worldwide Clinical Studies using Stem Cells obtained from different sources

Improvement in clinical signs and symptoms

Majority of the patients treated with us have shown marked improvement reduction in inflammation of the liver and improved liver function test results. Find out how Stem Cell Therapy is improving the lives of patients suffering from Liver Diseases.

  • D K, Liver Cirrhosis Treatment

    Mr. D K had been a heavy drinker for the past many years resulting in his liver getting early signs of degeneration. His doctors ha told him that he is looking at a possibility of developing Cirrhosis soon and could ultimately end up needing a liver transplant in a few years time. Mr. D K decided that he wants to try regeneration of liver through stem cell therapy and contacted Advancells for help. Upon reading Delhi, India he underwent a battery of tests and finally underwent stem cell therapy. Although he was advised autologous bone marrow and adipose tissue stem cell therapy but since his platelet levels were very low, it was decided that he will get cord tissue Mesenchymal Stem Cells. An appropriate dosage of cells were injected via IV which the patient tolerated well.

TYPES OF LIVER DISORDERS

Fever
Fever

Fatigue
Fatigue

Loss of appetite
Loss of appetite

Nausea
Nausea

Vomiting
Vomiting

Abdominal pain
Abdominal pain


Abdominal swelling
Abdominal swelling

Visibly enlarged blood vessels beneath the skin surface
Visibly enlarged blood vessels beneath the skin surface

Red palms
Red palms

Yellowing of the skin and eyes
Yellowing of the skin and eyes

Enlarged spleen
Enlarged spleen

Excessive fatigue
Excessive fatigue


Excessive fatigue
Excessive fatigue

Weight loss
Weight loss

High blood pressure
High blood pressure

Confusion or drowsiness
Confusion or drowsiness

Passing blood through stool
Passing blood through stool

Swelling in the ankles and tummy
Swelling in the ankles and tummy


Itchy skin
Itchy skin

Yellowing of the skin
Yellowing of the skin

Vomiting blood
Vomiting blood

Bleeding and/or bruising continuously
Bleeding and/or bruising continuously

Loss of sex drive
Loss of sex drive

Swollen legs or tummy from a build-up of fluid
Swollen legs or tummy from a build-up of fluid


Fatigue
Fatigue

Abdominal symptoms
Abdominal symptoms

Abnormal blood vessels on the skin
Abnormal blood vessels on the skin

Skin rashes
Skin rashes

Loss of menstrual blood
Loss of menstrual blood

An enlarged liver
An enlarged liver

CAUSES
Liver damage can be life-threatening, if not attended immediately. Most often liver damage is a gradual process, happening due to liver abuse over a period of time. However, there are certain acute conditions caused due to multiple cases of abuse. Accordingly, certain causes of liver disorders include:

CAUSES OF
LIVER DISORDER
  • Viral pathogenic infections causing inflammation
  • Long-term alcohol consumption leading to liver cirrhosis
  • Long-term consumption of oily, fatty food leading to liver damage and inflammation
  • Eating poisonous wild mushrooms
  • Autoimmune attack on the liver, leading to inflammatory damage of the virus
  • Acute fatty liver during pregnancy, causing excessive deposition of fat on the liver
  • Certain other overwhelming infections in the body can cause progressive liver damage
  • Drug overdose, including acetaminophen can damage liver function leading to progressive liver disorders.
  • Due to a rare genetic disorder named Wilson’s disease; the body’s copper-removing capacity is hampered leading to the deposition of copper in the liver causing its progressive damage.
SUPPORTIVE TREATMENT

Many studies have confirmed the application of various supportive treatments to aid in the therapeutic benefit of liver disorders. Apart from cell-based therapies using a combinational
approach of stem cells and exosomes, it is possible to reduce liver inflammation due to external abuse; promoting its functional regeneration. Moreover, the liver is the body’s only organ with self- regeneration capacity due to the presence of residual liver stem cells and hepatocyte progenitor cells. Accordingly, the holistic approach offering effective rehabilitation therapies can speed up its regeneration capacity.

Hyperbaric Oxygen Therapy
Hyperbaric Oxygen Therapy

Physiotherapy
Physiotherapy

Diet/Nutrition
Diet/Nutrition

Psychological counseling
Psychological counseling

OUTCOMES

As discussed previously, various studies have confirmed how a combination approach using stem cell therapy and exosomes is highly effective in minimizing inflammation and regularizing immune factors to support the functional restoration of the liver. Accordingly, the assessments done on the basis of extensive data collected from a large number of clinical investigations have proven that

Worldwide Clinical Studies using Stem Cells obtained from different sources

Improvement in clinical signs and symptoms
TESTIMONIAL

Majority of the patients treated with us have shown marked improvement reduction in inflammation of the liver and improved liver function test results. Find out how Stem Cell Therapy is improving the lives of patients suffering from Liver Diseases.

  • D K, Liver Cirrhosis Treatment

    Mr. D K had been a heavy drinker for the past many years resulting in his liver getting early signs of degeneration. His doctors ha told him that he is looking at a possibility of developing Cirrhosis soon and could ultimately end up needing a liver transplant in a few years time. Mr. D K decided that he wants to try regeneration of liver through stem cell therapy and contacted Advancells for help. Upon reading Delhi, India he underwent a battery of tests and finally underwent stem cell therapy. Although he was advised autologous bone marrow and adipose tissue stem cell therapy but since his platelet levels were very low, it was decided that he will get cord tissue Mesenchymal Stem Cells. An appropriate dosage of cells were injected via IV which the patient tolerated well.

Must Read Articles on Liver Cirrhosis Disease

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Stem Cell Therapy: A Hope for Liver Transplants Patients
Stem Cell Therapy: A Hope for Liver Transplants Patients

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Meta-analysis of Liver Disorders using stem cell therapy

Several clinical investigations have confirmed that stem cell and exosome therapy is safe and effective for patients with liver disorders. The meta-analysis was done on the basis of 9 clinical investigations, out of which 2 studies infused stem cells through portal veins, 3 studies infused cells through the hepatic artery, and 4 studies applied stem cells through peripheral veins. The assessment confirmed that mesenchymal stem cells injected through the hepatic portal vein showed better improvement, as compared to other stem cells. In general, the meta-analysis confirmed that the outcome of cell-based therapies for liver diseases is desirable when assessed for 12 weeks.

Recent Liver Diseases Patient Case Stories

Majority of the patients treated with us have shown marked improvement reduction in inflammation of the liver and improved liver function test results.

Find out how Stem Cell Therapy is improving the lives of patients suffering from Liver Diseases.

FAQs

 
Advancells is a strong advocate of greater transparency in medical procedures in general and Stem Cells Procedures in particular. As a part of our effort of bringing transparent procedures to our clients, we provide each client a Third Party Certificate (from an internationally accredited lab) for the cell count and viability of the cells that we are able to process from the autologous cell source of the patient. To view the sample copy of the certificate  click here

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