Mesenchymal Stem Cell Therapy

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    What is Stem Cell Therapy?

    Stem cell therapy, a branch of regenerative medicine, aims to repair damaged cells in the body by reducing inflammation and modulating the immune system. This approach presents a viable treatment option for a range of medical conditions. Stem cell therapies have shown promising results in addressing autoimmune, inflammatory, neurological, orthopedic conditions, and traumatic injuries. Ongoing studies explore their potential applications in treating conditions such as Parkinson’s Disease, Multiple Sclerosis, Lupus, COPD, Autism, ALS, Stroke recovery, and more.

    Although stem cell therapies may not provide a definitive cure for these conditions, their primary goal is to stimulate the body’s natural healing processes, thereby alleviating symptoms and prolonging periods of relief.

    What Are Stem Cells?

    Stem cells are unspecialized cells of the body with the potential of self-renewal and differentiation. Our body starts with totipotent cells, growing up to three layers (endo, ecto, and mesoderm) having pluripotent stem cells. As an adult, the body has reserves of multipotent and unipotent stem cells.


    Why Are Stem Cells Getting Attention?

    • Increased understanding of diseases by studying stem cells and their maturation.
    • Stem cells can be programmed to differentiate into specific cells for tissue-specific regeneration.
    • Many patients with diabetes, Parkinson’s disease, ALS, Alzheimer’s disease, osteoarthritis, autism, etc. have seen improvements with stem cell therapy approaches.
    • Stem cells have the potential to grown tissues for transplants in regenerative medicine.
    • Drug safety testing research can use stem cells in 3D culture models.

    Stem Cell Types and Sources

    There are different types of stem cells, each with distinct properties and potential applications. Adult stem cells, also known as somatic or tissue-specific stem cells, reside in various tissues throughout the body and play a vital role in tissue maintenance and repair. Examples of adult stem cells include hematopoietic stem cells found in bone marrow and mesenchymal stem cells (MSCs) found in various tissues, including Wharton’s Jelly, adipose tissue, and bone marrow. Induced pluripotent stem cells (iPSCs) are generated by reprogramming adult cells back into a pluripotent state, resembling ESCs in their ability to differentiate into different cell types. They offer a potential alternative to ESCs while avoiding ethical concerns associated with embryo usage. Understanding the different types and sources of stem cells is crucial for harnessing their regenerative potential and advancing therapeutic applications in various fields of medicine.


    Stem Cells Vs Normal Cells

    Stem cells and normal cells have complementary functions in the body’s maintenance and repair processes. While normal cells perform specific tasks and have specialized roles, stem cells serve as a reserve that can generate fresh cells and replace those that are damaged or aging.

    What Is Stem Cell Treatment And How Does It Work?

    Stem cell therapy or stem cell treatment promotes repair response of injured tissues by using stem cells or regenerative derivatives of the stem cells like growth factors etc. Stem cell treatment is safe and effective and many doctors are quickly taking up stem cell therapy as alternative medicine during early intervention. Doctors generally use three main sources of stem cells for therapy: adipose tissue, bone marrow, and umbilical cord blood. Stem cells are extracted from these tissues and characterized before sorting. Researchers grow stem cells in optimized lab settings and these cells are programmed or manipulated into specific body cells like muscles, nerve cells, bone cells, etc. These specialized autologous stem cells can be implanted in a person or at times, mesenchymal stem cells or hematopoietic stem cells can be transfused in the patient with derivates for treatment. Cell regeneration therapy has been used previously in blood disorders but in recent times, advanced cell technology is used for arthritis, diabetes, anti-aging, and neuro-disorders. Several disorders of degenerative nature do not have a cure or at least their conventional treatment methods only hint at curing the symptoms rather than target the underlying degeneration. Therefore, stem cell therapy comes up as a silver lining for these disorders as they limit the disease progression naturally besides promoting repair of the tissue damage, hinting at damage reversal.

    Stem Cells Vs Normal Cells

    Normal Cells

    Normal cells, also known as somatic cells, are differentiated cells that have specific roles and functions in different tissues and organs. They are specialized to perform specific tasks such as carrying oxygen (red blood cells), transmitting nerve impulses (neurons), or secreting enzymes (pancreatic cells). Normal cells have limited abilities to self-renew and regenerate.

    Stem Cells

    Stem cells are undifferentiated cells with the unique ability to differentiate into multiple cell types and self-renew through cell division. They serve as a repair and regeneration system within the body. Stem cells can be found in various locations, including embryonic tissue, fetal tissue, and adult tissues. Adult stem cells found in various tissues, have a more limited differentiation potential but are essential for tissue maintenance and repair.

    How Does Stem Cell Therapy Work?

    Stem cell therapy is a medical approach that harnesses the regenerative potential of stem cells to treat various diseases and conditions. Stem cell therapy process involves the administration of stem cells to targeted areas of the body to promote tissue repair and regeneration. Here is an overview of how stem cell therapy works:

    • Source Identification: Stem cells can be obtained from various sources, such as bone marrow, adipose tissue, or umbilical cord blood. The specific source is chosen based on factors like accessibility, abundance, and the type of stem cells required.
    • Harvesting and Isolation: Stem cells are extracted from the chosen source using minimally invasive procedures. The cells are then isolated and prepared for administration.
    • Administration: The isolated stem cells are introduced into the patient’s body through different methods, depending on the condition being treated. They can be delivered directly to the affected area, injected into the bloodstream, or guided to specific tissues using imaging techniques.
    • Differentiation and Integration: Once inside the body, the stem cells have the potential to differentiate into specialized cell types. They can replace damaged or dysfunctional cells, stimulate the growth of new blood vessels, and modulate the immune response. This process aids in tissue repair, regeneration, and functional restoration.
    • Monitoring and Follow-up: After the stem cell therapy, patients are closely monitored to assess treatment response and potential side effects. Follow-up evaluations help determine the effectiveness of the therapy and guide any necessary adjustments.

    Therapeutic Use of Stem Cell Therapy

    Stem cell therapy holds tremendous promise as a groundbreaking therapeutic approach that has the potential to revolutionize the field of medicine. By harnessing the unique regenerative properties of stem cells, researchers and medical professionals are exploring their therapeutic use in a wide range of conditions and diseases. Stem cells have the remarkable ability to differentiate into various specialized cell types, enabling them to replenish damaged or diseased tissues and promote healing. 

    Here is a list of diseases that have been explored for potential stem cell therapies:

    Neurodegenerative Diseases

    • Parkinson’s disease
    • Alzheimer’s disease
    • Motor Neuron Disease (MND)
    • Autism
    • Cerebral Palsy
    • Muscular Dystrophy

    Liver Diseases

    • Liver Cirrhosis
    • Hepatitis
    • Fatty Liver

    Autoimmune Disorders

    • Multiple sclerosis
    • Diabetes
    • Lupus
    • Rheumatoid arthritis

    Eye Disorders

    • Age-related macular degeneration (AMD)
    • Retinopathy
    • Optic Nerve Atrophy

    Orthopedic Conditions

    • Osteoarthritis
    • Rheumatoid Arthritis
    • Sports/Knee Injury

    Lung Diseases

    • Chronic obstructive pulmonary disease (COPD)
    • Interstitial Lung Disease (ILD)
    • Long COVID

    Spinal Cord Injuries

    • Paraplegia
    • Quadriplegia
    • Spinal cord trauma
    • Paralysis

    Skin Diseases

    • Lupus
    • Ulcers
    • Skin Burns
    • Diabetic Foot

    Success Rate of Stem Cell Therapy

    The success rate of stem cell therapy can vary depending on several factors, including the specific disease or condition being treated, the type of stem cells used, the patient’s overall health, and the stage of the disease. Some other factors that can influence the success rate include the ability of the transplanted stem cells to engraft and differentiate into the desired cell types, the patient’s immune response, the persistence and long-term efficacy of the treatment, and the possibility of complications or adverse reactions.

    Success Rate Of Stem Cell Therapy In India

    Advantages of Stem Cell Therapy

    Stem cell therapy offers several potential advantages that make it a promising field of medical research and treatment:

    • Regenerative Potential: Stem cells have the remarkable ability to differentiate into various cell types and regenerate damaged tissues. This regenerative capacity holds great potential for repairing and replacing damaged or diseased cells and tissues in the body.
    • Versatility: Stem cells can be derived from various sources, including umbilical cord, and adult tissues such as bone marrow and adipose tissue. This versatility allows for different approaches and sources of stem cells depending on the specific condition being treated.
    • Reduced Risk of Rejection: Stem cells derived from the patient’s own body (autologous stem cells) can be used, reducing the risk of rejection or adverse immune reactions. This personalized approach enhances the safety and effectiveness of the treatment.
    • Potential for Personalized Medicine: Stem cell therapy holds promise for personalized medicine, as it allows for tailored treatments based on an individual’s unique needs, genetic makeup, and medical history. This individualized approach may lead to better outcomes and improved patient care.
    • Minimally Invasive Procedures: In many cases, stem cell therapies can be administered through minimally invasive procedures such as stem cell injections or infusions. This reduces the need for invasive surgeries and can lead to quicker recovery times and reduced risks associated with more invasive treatments.
    • Treatment of Previously Incurable Diseases: Stem cell therapy offers hope for conditions that were previously considered incurable or had limited treatment options. This includes degenerative diseases, neurological disorders, and certain types of cancer, among others.

    Is Stem Cell Therapy Safe or Not?

    Stem cell therapy presents numerous favorable safety aspects due to no side effects or risk of rejection. By utilizing a patient’s own autologous stem cells, the risk of immune rejection is eliminated since the cells originate from their own body. Procedures with a well-established track record, like hematopoietic stem cell transplants, have demonstrated enduring safety records. Stringent regulations are in place to guarantee the ethical and secure application of stem cell therapies. Thorough patient assessments conducted by proficient medical teams aid in evaluating suitability and minimizing potential risks. Continuous monitoring and regular follow-up procedures ensure prompt identification of any adverse effects that may arise.


    Current Status of Stem Cell Research

    Researchers continue to explore various types of stem cells, including embryonic stem cells, induced pluripotent stem cells, and adult stem cells, each with its unique advantages and challenges. Significant progress has been made in understanding the mechanisms that govern stem cell differentiation and self-renewal, paving the way for targeted therapies and regenerative medicine approaches. Stem cells hold promise in areas such as neurodegenerative diseases, cardiovascular conditions, organ transplantation, and tissue engineering.

    However, challenges persist, such as optimizing differentiation protocols, ensuring safety, addressing ethical concerns, and establishing standardized guidelines. With continued dedication and scientific advancements, the future of stem cell therapy holds immense potential to revolutionize healthcare and contribute to improved patient outcomes in the future.

    Cost of Stem Cell Therapy

    The cost of stem cell therapy can vary depending on several factors, including the type of stem cell treatment, the specific condition being treated, the number of sessions required, and the location where the therapy is administered. Stem cell therapy can be a significant investment due to the complex procedures involved and the need for specialized medical expertise.

    However, compared to Western countries, India has emerged as a popular destination for stem cell therapy due to its reputation for providing high-quality medical care at a relatively lower cost. Many individuals seeking stem cell therapy find that India offers more affordable options without compromising on the quality of treatment. It’s crucial for individuals considering stem cell therapy to thoroughly research and consult with reputable medical institutions and professionals to understand the potential costs involved and make informed decisions based on their specific circumstances.

    Affordable Stem Cell Therapy in India

    It is important to note that determining the “best” stem cell therapy clinic in India can be subjective and may vary depending on specific medical conditions and individual needs. Advancells is a prominent stem cell therapy provider in India, recognized for its advanced laboratory facilities and innovative treatments. We provide personalized therapies for a wide range of medical conditions, including neurodegenerative disorders, orthopedic conditions, and autoimmune diseases.


    In conclusion, stem cell therapy presents a remarkable frontier in the field of medicine, offering the potential for revolutionary treatments and regenerative solutions. With the ability to replenish damaged tissues, promote healing, and potentially modify the course of diseases, stem cell therapy holds promise for a wide range of conditions, from neurodegenerative disorders to orthopedic injuries and beyond.

    Ongoing research, advancements in technology, and stringent regulations contribute to the continuous growth of this field, ensuring safety, efficacy, and ethical practices. While challenges and complexities exist, the potential for improved patient outcomes and enhanced quality of life is undeniable. As stem cell research continues to progress, it opens doors to a future where previously incurable conditions may find viable treatments and where the power of regenerative medicine transforms lives.

    Frequently Asked Questions about Stem Cells

    Advancells is a strong advocate of greater transparency in medical procedures in general and Stem Cells Procedures in particular. We do not have any medical doctors on our payroll and we do not give any medical opinion or conduct medical procedures at our premises. We are a CGMP compliant cell manufacturing facility and provide each client a Third Party Certificate (from an internationally accredited lab) for the cell count and viability of our cells. View sample Certificate