Stem cells for Sports Injury Treatment

A paradigm shift in cellular therapies for regenerative medicine

Employing novel mesenchymal stem cells, their signalling mediators and secretome therapies to modulate the immune system and treat pain

Our platform leverage stem cells as cellular pharmacies and utilizes secretome as a therapeutic agent

Sports Injury Stem Cell Treatment

Sports injuries have common occurrence in professional sports, due to increased wear and tear of the locomotive tissues requiring immediate medical attention. Due to overuse, sudden trauma or injuries; the muscles, ligaments, tendons or cartilages can release certain chemicals initiating an inflammatory response. This is in turn characterized by pain, localized sweating, redness ultimately leading to the progressive degeneration to the extent of ending the player’s career.
Knee injury treatment generally take quite longer time to recover and stay pain-free. In case of severe injuries, in the conventional medical practice, surgical correction or reconstruction of torn tissue is the only available option for knee injury treatment that may be associated with severe other complications. The advancements in regenerative medicine, have found out an anecdote in terms of stem cells treatment of knee injury for retaining lost functions of the tissue as well as promoting faster healing through regulation of various immune reactions.

Some of the commonly associated problems in sports injury:

Achilles Tendon Injury

Achilles tendon is the largest tendon present in body. It is a strong fibrous cord stretching from the bones of heel to the calf muscles. It is a springy band of tissue at the back of the ankle, above the heel, allowing the toes to point towards the floor and to be raised on tiptoes. This tendon is very prone to injury though because of poor blood flow causing disrupted healing. Rupture or injury to the tendon happen due to a sudden increased stress and could be mild or moderate causing inflammation or stiffness in the leg. Tendon rupture mostly happens within 6 centimeters of the point where the tendon is attached to the heel bones. After being injured, a person would be unable to bend the foot downward or push off the injured leg while walking.

Knee/ Ligament Injuries

Ligament is a short band of tough fibrous connective tissues made up of long, stringy molecules connecting the bones in body to other bones and around joints. A ligament could be injured through a sudden, sharp change in direction or landing a wrong jump or a blunt force hit to the knee. The injury happens due to sudden movement at a high speed. Also weakness in muscles or non-coordinated movement leads to sprain or tear in ligament. There are basically four ligaments in the knee that are very sensitive to injury: Anterior Cruciate Ligament (ACL), Posterior Cruciate Ligaments (PCL), Lateral Collateral Ligament (LCL), and Medial Collateral Ligament (MCL). Ligaments control the mobility of a joint and preventing certain movements.

Ankle Injuries

Ankle injuries are classified according to the type of tissues injured. Injury in bones is fracture, injury in ligament is sprained ankle, injury in muscles is strain or tear, injury in tendons is tendinopathy/tendonitis.  The ankle joint is a point where three bones meet- the tibia (shin), fibula (thin bone outside the leg), and the thalus (ankle bone) above the heel. Ankle joint is passively stabilized by ankle ligaments that are semi-elastic bands made up of connective tissues limiting the normal motion of the ankle joint. The tendons and muscles of ankle control the movement of ankle joint, protecting it from injury by stabilizing the ankle joint and preventing overstretching of ligaments. In the ankle, two tendons are very sensitive and often get strained. One of them is the peroneal tendon that stabilizes and protects the ankle and can become inflamed due to overuse or trauma. Acute tendon tears are caused by sudden trauma or force. Tendinitis is a condition of inflammation of the tendons. Tendinosis is a condition when microscopic tendons accumulated over time; do not heal from tears because of being repeatedly over stretched. Tendons could rupture too and subluxation is a condition when tendons get displaced from their place. Traumatic ankle ligament sprains, ankle fractures (broken bones), tendinopathies, degenerative arthritis, biomechanical disorders are the most frequent reasons of ankle pain.

Rotator Cuff Tear

The Shoulder is a ball-and-socket-joint: the ball or head of upper arm fits into a shallow socket in the shoulder blade. Shoulder consists of 3 bones: upper arm bone (humerus), shoulder blade (scapula), collarbone (clavicle). Rotator cuff keeps the arm in the shoulder socket. Rotator cuff is made of four muscles that unite together as tendons forming a covering around the head of the humerus and helping in raising and rotating the arm and stabilizing the shoulder joint. Bursa, a lubricating sac, present in between the rotator cuff and the bone on top of the shoulder(acromion), helps in rotator cuff tendons to glide freely while moving the arm. Inflammation or pain is caused in bursa due to injury in the rotator cuff tendons.

Tennis Elbow

It is an inflammation of the tendons called tendinitis. Tendons are a band of tough tissues, joining the forearm muscles on the outside of the elbow. Pain occurs when the tendons are overloaded by repetitive motions of the wrist and arm. Repetitive gripping activities especially involving the thumb and first two fingers could lead to tennis elbow. Elbow joint is composed of 3 bones: the upper arm bone-the humerus, the two bones in the forearm-radius and ulna. There are bony bumps at the bottom of the humerus-epicondyles and on the outside i.e., at lateral side-lateral epicondyle. Muscles, ligaments and tendons are keeping the elbow joints together. The forearm muscles extend the wrist and fingers. The forearm tendons (extensors) attach the muscles to bones. Extensors attach on lateral epicondyles. Extensor Carpi Radialis Brevis (ECRB) is the tendon involved with tennis elbow. In lateral epicondylitis, the dominant arm is mostly affected.

Stem Cell Therapy for Sports Injury: Advancells Protocol

At Advancells, we aim at barring the progression of the damage with more emphasis on repealing of the damaged tissue. Our unique treatment pattern is designed considering the pathophysiology of each injury. Advancells is excited by the prodigious prospects of stem cells in treating various degenerative conditions, hence we are constantly updating our knowledge and technology to suit unique specifications of each patient for stem cell therapy of knee injury.
With extensive research these challenges are now comprehensible to therapeutic ventures resulting in new treatments of knee injury using autologous treatment/allogenic transplant for adipose-derived mesenchymal stromal cells treatment and bone marrow stromal cells treatment. This new insight on the treatment of sports injury has helped in identifying the potential to overcome knee injury with stem cells, primarily using autologous stem cell transplant in form of hematopoietic stem cell transplant or mesenchymal stromal cells treatment.
Our top priority is to provide a very comprehensive, tailor-made treatment option, which would facilitate maximum recovery. That is the reason, we have chosen patients own platelet rich plasma as a strong vehicle, allowing error free deposition of stem cells at the site of injury. Various clinical investigations have identified a strong communication and healing potential of this growth factor concentrate that would elicit major cascade of signalling pathways in stem cells and  promote faster regeneration of damaged tissues. For all sports related injuries, we have come up with the advanced and most potent protocol, wherein patients own stem cells are being obtained through Adipose tissue/fat, and activated through PRP; to be able to infuse directly at the site of injury.

 

Stem Cell Treatment of Sports/Knee Injury at Advancells is divided into 4 Steps

 

Treatment Qualification

Source Extraction

Processing of stem cells

Re-infusion

Causes OF Sports injury

Fatigue

Muscle imbalances

No protective gear

Older age

Poor sports technique

Symptoms OF Sports injury

Bruising

Difficulty in lifting weight

Pain and swelling

Joint stiffness

Lmited range of motion

Muscle spasms

Why Choose Stem Cell Therapy?

100% Safe

Targeted delivery

Minimally-invasive

natural

nerve

regeneration potential

Must Read Articles on Stem Cell Therapy for Knee Injury/ Sports Injury

Stem Cells for Knees: Hopeful Treatment In India
Stem Cells for Knees: Hopeful Treatment In India

Over 25% of adults in the US are affected by knee pain, and it can affect individuals of any age group. Sometimes due to overburdening, unexpected trauma, or injuries; the muscles, ligaments, tendons, or cartilages can secrete certain biochemicals that result in an...

Advancells is a strong advocate of greater transparency in medical procedures in general and Stem Cells Procedures in particular. We do not have any medical doctors on our payroll and we do not give any medical opinion or conduct medical procedures at our premises. We are a CGMP compliant cell manufacturing facility and provide each client a Third Party Certificate (from an internationally accredited lab) for the cell count and viability of our cells. View sample Certificate
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