Stem Cell Treatment for Multiple Sclerosis



Multiple Sclerosis

Multiple Sclerosis, often belongs to the prevailing neurological disorders of the central nervous system; mostly affecting middle age people. Although the cause of the disease is still unknown, it has been proved by the scientists that it is generally triggered by as yet unidentified environmental factor in a person, who is genetically predisposed to the respondent.

Multiple Sclerosis is generally referred to as an immune mediated process, in which an abnormal response of the body’s immune system is directed against the central nervous system, which accounts for brain, spinal cord & optic nerves. The exact antigen or target that the immune cells are sensitized to attack remains unknown. Possibly, this may be the reason why MS is more known to be immune mediated disease rather than autoimmune disease.

Within our central nervous system, there is a network of cells known are neurons which transmit information from the brain to other organs of the body. These cells are covered with the insulating materials to protect them from the outer sock. These insulating outer materials are known as myelin sheaths, the damaged myelin sheath forms a scar tissue or sclerosis, which gives the disease its name. On a generalized note, people with MS may experience one of four disease courses, which can be mild, moderate or severe.

As a matter of fact, Multiple Sclerosis symptoms are variable and unpredictable. It is known that two people cannot experience exactly the same symptoms, even for that matter each person’s symptoms will not also be the same but it will fluctuate over the period of time.

Thus, considering these facts, some of the commonly associated symptoms have been listed out here

  • Fatigue
  • Numbness or Tingling
  • Weakness
  • Dizziness or Vertigo
  • Walking Difficulties
  • Spasticity
  • Vision Problems
  • Bladder Problems
  • Speech Problems
  • Swallowing Problems
  • Tremor, Seizures, Breathing Problems, Itching
  • Headache, Hearing Loss
  • Repeated urinary tract infection due to bladder dysfunction
  • Pressure sores due to immobility
  • Depression

This is the chronic condition associated with narrowing of vein in the neck and the chest region, carrying blood away from the brain and spinal cord. When the blood flow is slow or obstructed, it backs up into the brain and the spinal cord leading to oxygen loss and severe iron deposits in those vital areas of the body. Thus the inverted flow of blood rapidly results in cerebral edema, affecting the blood-brain barrier to a great extent. This restriction of the blood vessels averts blood from flowing rapidly enough, leading to autoimmune swelling which hampers the brain as well as the shielding myelin nerve coating.

Broadening of the stenotic (narrowed) veins augments the smooth flow of blood through them. This helps in easing the back-pressure and abolishing the inflammation, which is the main cause of the damage to the brain as well as the defending myelin.

The conventional treatment approach to treat MS mostly involved some oral medications to soothe from the problem or to avoid relapse followed by rehabilitation like physiotherapy or occupational therapy, etc. However the point here to be noted is that although patients are getting some relaxation from these treatments, it is not possible to alter the diseased condition and the patient has to stay in the same agony forever. Recently 100% of the cases of MS have been connected with a chronic condition known as CCSVI; which literally stands for chronic cerebro-spinal venous insufficiency.

List of diseases treated

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Stem Cell Treatment

Stem Cell Treatment For MS: Advancells Protocol

Currently, there are no specific treatments for Multiple Sclerosis, however, at Advacells, we are harnessing the power of body’s own very primitive cells- The stem cells, to regulate and guide your immune system to distinguish self tissue from non self tissue and thereby reducing the autodestruction of the myelin sheath. These stem cells can also help in regenerating lost neurons, and smoothened the signalling process.

Advancells is excited by the prodigious prospects of stem cells in treating various diseases, hence we are constantly updating our knowledge and technology to suit unique specifications of each patient. Our principle objective has always been a cessation of disease progress and easing the quality of life to a considerable extent. We are always pledged to deliver safe treatment pattern, by offering "Autologous stem cells from your own Bone Marrow/Adipose Tissue"

Our top priority is to provide very comprehensive, tailor made treatment pattern with the maximum recovery. As a part of our treatment, patient's stem cell are obtained from two sources adipose-derived stem cells (ASCs) and bone marrow-derived stem cells (BMSCs). Sometimes we may use a combination of both, depending upon the assessment.

Step 1- Qualification For The Treatment

A safety and efficacy assessments will be prescribed by our experts in order to investigate the stage of severity and qualify the patient for the treatment. Following pretreatment assessments can be suggested depending upon the patient’s medical and family background:

Pre-Treatment Assessments

  • Infectious Disease Testing
  • Routine Blood tests
  • Physical Examination
  • X ray

Pre-Operative Procedure

  • MRI
  • CT-Scan
  • Neurophysiology
  • Echo, Doppler Test
  • CT, Venography
  • Medical Neurological Reports & History

As per these results, the patient will be counseled further for final decision of protocol.

Step 2- Source Extraction

With the physician’s approval and guidance, the source from which stem cells are to be collected is decided. In general patient can be prescribed, stem cells isolated from Bone Marrow or Adipose Tissue, as these are the most potent autologous sources available. However, in certain cases, both sources can be utilized for a better outcome. Doctors can also suggest stem cell stimulation therapy for some, depending upon the severity and requirement.

The specified amount of samples will be extracted from the patient’s own body on the intimated date and time, with the application of local anesthesia. The entire procedure takes around 7-8 hrs, however, in case of extracted from both the sources the patient has to be with us for a little longer time.

If you are curious to know more about the procedure, kindly refer our detailed snapshot below:

stem cell treatment for ALS

Step 3- Laboratory Processing

The extracted sample, will be sent to the government approved cGMP laboratory for processing. The sample processing will be done in a state of the art class 10,000 clean room in compliance with the ISO and GMP standards.

The sample will undergo minimum manipulation in our complete automated Sepax technology to be enriched with the pure population of stem cell culture. The isolated stem cells will be characterized for quality, purity and viability.

The client will be given a third party certificate from Internationally Accredited Lab for the quality purpose.

The client will be given a third party certificate from Internationally Accredited Lab for the quality purpose.

Step 4- Stem Cell Implantation

Once stem cells are enriched and ready to be injected back into the body, we have worked on different modes of implanting them. However, depending upon the patient’s physiological and mental well being, one of the following will be finalized by our experts.

In case of CCSVI patients, stem cells are infused through special and very critical mode known as liberation Angioplasty & Angiography.

  • Liberation Angioplasty:- It is a very critical process, using X ray scanning to guide the catheter with the balloon tip in the affected area.
  • Angiography:-It is the process of injecting stem cells in the pulmonary artery via a catheter guided through the heart under high-tech X ray navigation.

Follow up Treatment

Post treatment, the patient will be asked to visit the doctors for reclamation therapies such as Physiotherapy, patients counselling etc. for accelerated recovery.



Multiple Sclerosis Stem Cell Treatment Results

14 male and 36 female patients were treated with the MS stem cell treatment and post treatment, they reported with their answers of the questionnaire.

The average age of the patients were around 48 years before the Multiple Sclerosis treatment and the treatment took an average time span of around 5 months.

Improvement was reported in 25 patients while no change in 18 patients and normal development of the disease in 7 patients.

68.8% of the patients reported development in muscle strength while 78.9% reported spasticity of the limbs and 55.6% reported of better coordination of their limbs.

50% and 25% respectively reported of being able to stand alone and walk without any help.

Improved vision was reported by 57.1% of the patients, while 47.1% and 28.6% of them reported improved bladder and bowel control.(Read more...)

Patient's Stories

Multiple Sclerosis/CCSVI

Nicole Corry, 45 years, Multiple Sclerosis

"...I am still walking better, feel well and positive and less fatigued."

Russel Miller, 53 years, Multiple Sclerosis

"...My quality of life has improved dramatically"

Kerry O'Connor, 59 years old, Multiple Sclerosis

"...I can stand for a longer time on my legs, my balance has improved, my walking has slightly improved and I can walk for longer periods of time unaided."

Caroline van der Lee, 37 years, CCSVI

"...Ms. Van Der Lee is now has better balance and can walk about twice as fast as before ..."

Stephan Steghaus, 47 years, MS - CCSVI

"...I feel 100% perfect, and wonder - did I really have this condition?"..."

Nicole Corry, 45 years, Multiple Sclerosis

"....Six months on, I am stable, with no new symptoms. I am still walking better, feel well and positive and less fatigued. I am even back to working as a volunteer two days a week..."

Russel Miller, 53 years, Multiple Sclerosis

"...My quality of life has improved so dramatically..."

Eileen Connolly, 58 years, Multiple Sclerosis

"...I can now lift my arm and have complete range of movement"..."

Laraine Sheers, 65 years, Multiple Sclerosis

"...I am now back home and astounded at the first, very obvious result I had which was being able to control my right foot properly when driving my car..."

Kerrie O'Connor, 59 years, Multiple Sclerosis

"...I have been home now for nine weeks and I feel so much better. I can stand for a longer time on my legs, my balance has improved, my walking has slightly improved and I can walk for longer periods of time unaided. & I look healthy once more..."

Ray Burrill, 59 years, Multiple Sclerosis

"...I notice showering, dressing, cutting nails and buttoning shirts are easier after stem cells treatment."

Alison French, 35 years, Multiple Sclerosis

"...My posture is straighter; not so much slouching anymore and I can get in and out of bed easier. I have colour in my face. I think I got a little taller as well; little subtle changes that have helped ...."

David Kannenberg, 54 years, Multiple Sclerosis

"...I have regained full mobility in my legs below the knee after stem cells treatment."

Philippe Daigueperce, 53 years, Multiple Sclerosis

"...After treatment, I could immediately see the results: static equilibrium back to normal and incontinence disappeared...."

Click to view or print complete MS results, including graphs (pdf)



Multiple Sclerosis Treatment Video
Multiple Sclerosis Treatment Video
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Frequently Asked Questions

  • Why is MS so difficult to diagnose?
  • The diagnosis of MS is very challenging at an early stage because symptoms may be very non specific and indicative of other diseases of the central nervous system. The early symptoms are very temporary causing no significant damage and hence are most of the times ignored easily by the people. Additionally, as such, no specific lab test is being used, apart from MRI; which can be significantly helpful in diagnosis. The complete diagnosis is always proportional to the expert based on the criteria.
  • Is MS contagious or inherited?
  • No, MS is not contagious neither it is directly inherited. Studies have indicated a mixed effect of both genes and environmental factors on development of MS. Research has evidently suggested that susceptible individuals may have a familial genetic contribution for MS, however, these individuals need to encounter some triggering factor from the environment to actually develop MS. The research is still underway to pinpoint the exact location of causative gene, its environmental cause, prevention and better treatment.
  • Is MS fatal?
  • In general MS is not considered a fatal disease, but the quality of life can be significantly affected in patients suffering with MS. As such there is no known full proof treatment available to reduce the sufferings. However, many therapeutic and technological advances are made in the field of stem cells to find a cure for the disease.
  • Can stem cell treatment, reverse my damage?
  • Yes, stem cells are the pristine cells of the body, which can give rise to many different types of cells upon proper signalling. These cells have been exploited successfully to differentiate into neurons. They have been isolated from the very own potent sources of our body known as Bone Marrow and Adipose Tissues. They can be minimally manipulated and implanted back into the body to promote neuroregeneration. They have also identified to be an effective guiding immune system to distinguish self tissue from the non self, thereby reducing further destruction.
  • Where can I get more information about Disease?
  • Please go through, our treatment brochures for other MS related information.


What can you expect?

Many patients after stem cell treatment reported to be exhibiting :

  • Rapid improvement of patient’s psycho-emotional condition
  • Most of the patients reported early improvements to decrease of weakness, increased energy, improved appetite and feel good effect
  • Some of the patients have observed to be exhibiting, deeper psychosomatic changes such as decrease depression, phobias and anxiety, gained more confidence, increased capacity and improved concentration.
  • During the follow up period, many of them reported, complete restoration of eyesight, improved mental and physical balance, and complete disappearance of depression.
  • Patients with primary progressive MS, have exhibited, the complete stoppage of MS.
  • However, a complete restoration of the central nervous system, is the prolonged process and requires lots of patience and repetition of treatment if required or suggested.

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