Stem Cell Therapy for Kidney Disorder
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Stem Cell Therapy For Kidney Disorder: Advancells Protocol
At Advancells, we aim on barring the progression of the diseased condition with more emphasis on repealing of the damaged tissue. That can certainly be fulfilled with the invention of stem cell therapy. These stem cells can be directly employed at the site of kidney damage with the catheter based injections, wherein they can facilitate regeneration of damaged nephrons by producing new podocytes, thus aiding in Kidney failure treatment. This strategy of using your own cells can also be helpful to reduce the risk associated with the immune rejection in terms of organ transplantation.
After the detailed study and research we would like to offer; a treatment regimen for kidney disorders in terms of “Autologous Stem Cells isolated from Bone Marrow/Adipose Tissue“. Our top priority is to provide very comprehensive, individualized treatment pattern which is best suited for the patients undergoing treatment. As a part of our treatment, patient’s stem cell are obtained from two sources adipose-derived stem cells (ASCs) and bone marrow-derived stem cells (BMSCs). Sometimes we may use a combination of both, depending upon the assessment.
Step 1- Qualification For The Therapy
A safety and efficacy assessments will be prescribed by our experts in order to investigate the stage of severity and qualify the patient for the treatment. Following pretreatment assessments can be suggested depending upon the patient’s medical and family background:
- Infectious Disease Testing
- Routine Blood tests
- Specific blood tests such as KFT
- Urine analysis
- Physical Examination
- Serum electrolyte modification
- Medical Nephrological Reports & History
As per these results, the patient will be counselled further for final decision of protocol.
Step 2- Source Extraction
With the physician’s approval and guidance, the source from which stem cells are to be collected is decided. In general patient can be prescribed, stem cells isolated from Bone Marrow or Adipose Tissue, as these are the most potent Autologous sources available. However, in certain cases, both sources can be utilized for a better outcome. Doctors can also suggest stem cell stimulation therapy for some, depending upon the severity and requirement.
The specified amount of samples will be extracted from the patient’s own body on the intimated date and time, with the application of local anesthesia. The entire procedure takes around 7-8 hours. However, in case of extraction from multiple sources the patient might need to stay for a little longer time.
If you are curious to know more about the procedure, kindly refer the detailed info graphic below:
Step 3- Laboratory Processing
The extracted sample, will be sent to the government approved cGMP laboratory for processing. The sample processing will be done in a state of the art class 10,000 clean room in compliance with the ISO and GMP standards.
The sample will undergo minimum manipulation in our complete automated Sepax technology to be enriched with the pure population of stem cell culture. The isolated stem cells will be characterized for quality, purity and viability.
The client will be given a third party certificate from Internationally Accredited Lab for the quality purpose.
Step 4- Stem Cell Implantation
Once stem cells are enriched and ready to be injected back into the body, we have worked on different modes of implanting them. However, depending upon the patient’s physiological and mental well being, one of the following will be finalized by our experts.
Intra-thecal Injection: Infusion of stem cells, through catheter directly into the renal artery.
Follow up Treatment
Post treatment, the patient will be asked to visit the doctors for reclamation therapies such as Physiotherapy, patients counselling etc. for accelerated recovery.
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"Advancells is a strong advocate of greater transparency in medical procedures in general and Stem Cells Procedures in particular. As a part of our effort of bringing transparent procedures to our clients, we provide each client a Third Party Certificate (from an internationally accredited lab) for the cell count and viability of the cells that we are able to process from the autologous cell source of the patient. To view the sample copy of the certificate "click here"
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