+91-9654321400 info@advancells.com

Ovarian rejuvenation with PRP (platelet-rich plasma) also known as autologous platelet-rich plasma ovarian rejuvenation therapy, is a fertility treatment that can help rebuild poor ovarian reserve in women who are having trouble getting pregnant due to ovarian insufficiency.

As a woman approaches menopause, her ovarian reserve, or supply of eggs, decreases. Considering the number of women deferring pregnancy and childbirth until later in age, attempting to conceive with a diminished ovarian reserve, a medical intervention that can increase ovarian function and reproductive health is therefore extremely important.

What is Ovarian Rejuvenation PRP?

PRP has been used in many various areas of medicine for approximately 30 years. PRP entails employing platelet-derived growth factors to boost the effectiveness of surgical treatments. PRP promotes new cell growth and improves blood circulation, which aids in healing.

Platelet-rich plasma PRP tries to perform two things in terms of fertility preservation. It boosts the number of eggs and the viability of the eggs and embryos, both of which are critical for reducing female infertility. PRP also appears to help prevent miscarriage by increasing the likelihood of a healthy embryo, which is the major consideration for patients This means that it allows women who have mainly relied on egg donation to conceive by using their own eggs instead of donor eggs.

How does PRP Ovarian Rejuvenation Work?

Autologous platelet-rich plasma treatment involves injecting autologous platelet-rich plasma into the ovary under ultrasound supervision. This platelet-rich plasma contains several growth factors that promote cell regeneration while also enhancing blood flow and vascularization.

While studies have demonstrated a good ovarian response to PRP injections, it is unclear if the eggs recovered after treatment were always present and were merely triggered by the treatment, or whether there was contact with ovarian stem cells that resulted in the production of more eggs. Harvard researchers discovered the existence of stem cells in the ovaries and their development into mature oocytes (egg cells) in mice. Stem cells have also been found in the human ovary, suggesting that they can be converted into eggs by growth factors found in the platelets and white blood cells of the people injected into the ovary.

How Much Does Ovarian Rejuvenation Last?

Because it is unknown how long ovarian rejuvenation would last, patients who have responded positively to treatment are recommended to undergo IVF, embryo preservation, or other procedures as soon as possible. Success rates vary, and some women may choose to try more than one treatment.

Due to the regenerative effect on egg cells, couples who were previously unable to conceive could be capable of conceiving naturally provided the fallopian tubes are clear and male fertility is not a concern. This eliminates the need for IVF therapeutic assessment and embryo transfer, which can enhance the likelihood of pregnancy and live birth even higher.

Recent research has proven that adult mice have ovarian stem cells that can develop into healthy eggs and give rise to healthy embryos. If human ovarian stem cells develop and can function similarly, PRP therapy may trigger them, and the results of ovarian rejuvenation may be considerably longer-lasting.