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Stem cell therapy for Lung Diseases

Stem Cell Therapy for Lung Disorders

In a day to day hectic schedule, one can barely register a nagging cough or slight wheeze, but considering the increasing evidences of lung diseases, it is indeed very critical to pay attention at even the most mild form of the symptom. Lung diseases are one of the most reaping medical conditions in the world affecting more than 10 millions people all over the world. They can arise due to problem associated with any part of the respiratory system. Some of the common type of lung diseases are: Interstitial Lung Disease (ILD),Chronic Obstructive Pulmonary Disease(COPD), Emphysema,etc.

Interstitial lung disease includes a group of over 200 lung diseases, like Idiopathic Pulmonary Fibrosis, Pulmonary Carcinomas as well as some atypical lung infections, such as pneumonia, tuberculosis, etc. The category is associated with extensive thickening of the supporting tissues between the air sacs (alveoli) of the lungs. The thickening can be due to inflammation, scarring, or extra fluid (edema). Some forms of interstitial lung disease are short-lived; others are chronic and irreversible. ILD Treatments are available in Stem Cell Therapy.

Chronic Obstructive Pulmonary disease also known as chronic obstructive airway disease is a type of lung disease characterised by progressively poor passage of airflow associated with difficulty in breathing; excessive cough and sputum are other common symptoms of COPD.

To understand COPD, we should first know how our lungs work. The inhalation and exhalation of air we breathe in is functioned by a network of tiny tubes in our lungs called Bronchioles or Airway tube. These tubes further end in a small round sac like structure called Air Sacs. Both these structures are elastic in nature. When we breathe in; each air sac fills up the air like a small balloon. Upon breathing out, air sacs deflate and the air goes out. The passage of the air flow is blocked because of the weakened elasticity, clogging of the airways due to excessive mucus production, etc. COPD develops slowly and worsen over the period of time. It may keep you handicapped for routine basic activities such as walking, cooking etc. Currently there is no cure in conventional medicine apart from some lifestyle changes and other medications. But with the unique regenerative properties of the stem cells it is possible to keep up with the destructive, inflammatory process caused by COPD.

Emphysema is a common type of COPD. In Emphysema the alveoli(air sacs) of the lungs, become damaged. The air sacs are the cells in the lungs where oxygen and carbon dioxide are exchanged, thus damage in this area causes the air to get trapped resulting in air sacs to expand and rupture. This causes a build up of carbon dioxide in the body. Emphysema is a progressive disorder with no treatment available in conventional medicine. But Stem Cell Therapy can help to slow the progression of the disease, treat the obstructed airways to relieve associated hypoxia and improve quality of life.


Major Manifestations of Lung Diseases, in patients include the following:

  • Chronic cough with a lot of mucus
  • Severe shortness of breath
  • Weight loss
  • Blue skin color, especially in the lips, fingers, and toes (called cyanosis)
  • Fluid buildup in the legs and feet (called edema)
  • Life-threatening COPD flare-ups
  • Lung function FEV1 of less than 30%, or of less than 50% along with chronic respiratory failure

The use of stem cells as a treatment regimen is quite appealing. As we know, these stem cells have strong regenerating properties. They can be rightly exploited for the protection of the lung tissue by suppressing inflammation caused by pollutants, acceleration of regeneration of airway tubes and air sacs. They can even efficiently trigger production of growth factors which will further facilitate regeneration. Stem cells are the mother cells of the body, mainly differentiating into the required types of cells upon channelizing through proper method. Research has evidently suggested that once inside the body, they can regeneration of new cells, removal of obstruction.

The stem cell therapy approach mainly focuses on delivering the sufficient number of Adult Autologous Stem Cells which will travel into multiple areas of the damaged parts.

List of diseases treated

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Stem Cell Treatment

Stem Cell Treatment For Lung Diseases: Advancells Protocol

We are exploiting the most potent stem cells isolated from patients own Bone Marrow or Adipose tissue or may be both depending upon the assessment. Our top priority is to provide very comprehensive, individualized treatment pattern which is best suited for the patients undergoing treatment.

Since body’s own cells are used the technique is very safe with no side effects, non invasive and effective.

Step 1- Qualification For The Treatment

A safety and efficacy assessments will be prescribed by our experts in order to investigate the stage of severity and qualify the patient for the treatment. Following pretreatment assessments can be suggested depending upon the patient’s medical and family background:

Pre-Treatment Assessments

  • Routine Blood Tests
  • Routine Urine Analysis
  • Infectious disease testing
  • Sputum Testing
  • Physical Examination
  • X Ray

Pre-Operative Assessments

  • Spirometry Test
  • Other Lung Functiona Test
  • MRI
  • CT scan
  • Medical History
  • Counselling

As per these results, the patient will be counseled further for final decision of protocol.

Step 2- Source Extraction

With the physician’s approval and guidance, the source from which stem cells are to be collected is decided. In general patient can be prescribed, stem cells isolated from Bone Marrow or Adipose Tissue, as these are the most potent autologous sources available. However, in certain cases, both sources can be utilized for a better outcome. Doctors can also suggest stem cell stimulation therapy for some, depending upon the severity and requirement.

The specified amount of samples will be extracted from the patient’s own body on the intimated date and time, with the application of local anesthesia. The entire procedure takes around 7-8 hrs, however, in case of extracted from both the sources the patient has to be with us for a little longer time.

If you are curious to know more about the procedure, kindly refer our detailed snapshot below:

Stem cell therapy  procedure for Lung Diseases

Step 3- Laboratory Processing

The extracted sample, will be sent to the government approved cGMP laboratory for processing. The sample processing will be done in a state of the art class 10,000 clean room in compliance with the ISO and GMP standards.

The sample will undergo minimum manipulation in our complete automated Sepax technology to be enriched with the pure population of stem cell culture. The isolated stem cells will be characterized for quality, purity and viability.

The client will be given a third party certificate from Internationally Accredited Lab for the quality purpose.

Step 4- Stem Cell Implantation

Once stem cells are enriched and ready to be injected back into the body, we have worked on different modes of implanting them. However, depending upon the patient’s physiological and mental well being, one of the following will be finalized by our experts.

Follow up Treatment

In a post treatment, care, the patient will be asked to visit the doctors after a specific period of time, for some rehabilitation programs, including strength, training exercises, oxygen therapy, counselling, Self regulation, evaluation and follow up.


Lung Diseases Treatment results

The majority of the patients treated by us have reported improved breathing function and stamina as well as great reduction in cough.They have observed to achieve emotional stability. Once treated patients are allowed to return to their home or hotel on the same day. Only in certain cases a days stay at the clinic will be advised.

Patient's Stories

Frank Wade, 68 years, COPD

"The physiotherapist is amazed at how well I am doing..."

Helio P., Pulmonary Hypertension

"There is always hope, so you may want to consider taking this treatment..."

"His medical exams are much better as well as his quality of life..."


Frequently Asked Questions

  • What is COPD?
  • COPD is a debilitating lung condition unabling patients to breath or enjoy life. Emphysema, Chronic Bronchitis, Chronic Obstructive Asthma are other common names for the same. It is the major cause of death worldwide. The sufferers may require a large amount of medical assistance.
  • What are the risk factors associated with the disease?
  • The most commonly listed risk factors associated with the disorder can be age, smoking, hereditary and environmental factors etc.
  • What are the current medical treatments for COPD?
  • COPD is the medical condition and therefore typically requires long term medications. The commonly used treatments for COPD are the use of bronchodilators, inhalers, oral steroidal medications, ventilators, surgery. However, these are either supplementary treatments or treatments with many side effects and hence for that matter an alternative treatment with complete reversal of damage is needed.
  • How is it diagnosed?
  • Commonly sputum tests, lung function tests are prescribed in order to assess that the person is suffering from COPD. Other than that chest X ray and lung scanning is also suggested for some of the patients.
  • How can stem cells be beneficial to treat?
  • Undifferentiated adult autologous stem cells are mutable and can metamorph into countless number of cells as per the requirement. This remarkable property of stem cells can be exploited for treating a variety of diseases. These cells can be isolated from the most potent sources of our own body known as Adipose Tissue and Bone Marrow. Upon implanting back into the body, these cells can rapidly multiply with the great speed to restore damaged cells, set up a microenvironment that can stimulate the secretion of growth factors, cytokines as a booster for regeneration.
  • Why is stem cells treatment better than conventional treatment approach?
  • Conventional treatment approach highly invasive associated with many side effects. Although stem cells can naturally heal the body from damage and regenerate tissues or cells to improve impaired functions. Additionally, since body’s own cells are used for repairing, the entire treatment is minimally invasive without any side effects.
  • Where can I get more information about Disease?
  • Please go through, our treatment brochures for other COPD related information.

What can you expect?

Many COPD patients after stem cell treatment reported to be exhibiting:

  • Improved Pulmonary Efficiency
  • Smoking Cessation
  • No need for surgery & inhalers
  • Deployment of COPD
  • Improved quality of life
  • Complete stoppage or progression of the disease