Acute liver failure (ALF) develops when a large number of liver cells die or sustain severe damage quickly. As a result, the liver is unable to function properly. The liver detoxifies the body, aids in controlling blood sugar levels, functions as a part of the immune system, and controls blood coagulation. Failure of the liver is an urgent situation that prompts medical attention.
Causes of ALF
There are several reasons for acute liver failure. One typical drug that can have an impact on how the liver functions are acetaminophen. This may occur if a person receives the incorrect dosage or ingests too much medication quickly. Other reasons for sudden liver failure include:
- Immunological Dysfunction
- Cardiovascular Issues
- Autoimmune Diseases
- Viral Infection
Symptoms of ALF
There are numerous conditions that might cause the earliest signs of liver failure. As a result, liver failure may be challenging to identify at first. Some of the common symptoms are:
- Loss of Appetite
- Swollen abdomen
- Hepatic encephalopathy
Stages of Liver Failure
Your liver will be swollen and sometimes painful in the early stages. You might not even be bothered by it.
- Liver Fibrosis:
Scarring will result from the inflammation if it is not treated. Your liver’s blood flow is restricted as scar tissue accumulates, which prevents the normal parts from performing their functions and forces them to put more effort.
- Liver Cirrhosis:
Your liver will either not function at all or will function poorly as the scar tissue takes over and leaves less and less healthy tissue to perform its functions.
- Liver Failure:
This is a catch-all word for a number of ailments, including swollen liver, internal bleeding, kidney function loss, fluid retention, and lung issues. It can only be cured through a liver transplant.
Treatment for Acute Liver Failure
When a liver transplant is indicated, patients with acute liver failure are frequently treated in the critical care unit of a hospital. Although your doctor may attempt to treat the liver damage immediately, treatment frequently entails managing problems and allowing your liver time for recovery. Some of the common treatment approaches include:
- Supportive Aid:
Hospitals can treat your symptoms up until the virus takes its course if a virus results in liver failure. Often the liver will heal itself in certain situations.
Acetaminophen overdose-induced acute liver failure can be treated with acetylcysteine. But you need to act swiftly. Additionally, there are drugs that can undo the harm caused by mushrooms or other toxins.
- Liver Transplant:
The first course of action may be to attempt to rescue the portion of your liver that is still functional if your liver failure is the consequence of long-term damage. You will require a liver transplant if that doesn’t work. Fortunately, this process works well most of the time.
Stem Cell Therapy for Acute Liver Failure
The diagnosis determines the course of treatment for liver disease. While some liver conditions can be addressed by making certain lifestyle adjustments, many severe conditions necessitate medicine or surgery. Regenerative therapies give individuals who have liver disease fresh hope for a better quality of life because of advancements in stem cell technology. Stem cell therapy for acute liver injury can promote normal liver function and lessen scarring.