As we age, wisdom and knowledge come, but that’s not all. Entering into twilight years can put a person at risk for certain health issues. Everyone will not get affected by the disease; however, by being aware of disease conditions we can be cautious towards health. Progressive supranuclear palsy (PSP) is one of the diseases that typically affects older people around the age of 60 and rarely occurs in people under the age of 40. PSP is a progressive brain disorder characterized by gait and balance difficulties and loss of eye coordination movements. As disorder name indicates that disease gets worsen (progressive) with time and can lead to life-threatening complications such as pneumonia and swallowing problems. PSP disorder is caused by the deterioration of cells in a certain part of the brain above the nerve cell cluster called nuclei (supranuclear) that control movement, vision, and thinking.
Symptoms
The characteristic symptoms of progressive supranuclear palsy include-
- Difficult to balance: The very first symptom of PSP is loss of balance while walking
- Difficult to control eye movements: People face problems involuntarily shifting their gaze vertically and people experience blurred vision.
Symptoms can get worsen with time and may include:
- Stiffness and awkward movements
- Falling could lead to head injuries, fractures, and other injuries
- Problems in swallowing
- Sensitivity to light
- Sleep disturbances
- Difficulties with memory, reasoning, problem-solving, and decision-making
- Depression and anxiety
Cause
The cause of progressive supranuclear palsy is unknown. Researchers have found that an abnormal amount of protein called tau is present in the deteriorating brain cells of people with progressive supranuclear palsy. Clumps of tau are also characteristic of other neurodegenerative disorders, such as Alzheimer’s disease. The inheritance of this disorder is also not clear till now.
Treatment
There is no cure for progressive supranuclear palsy, current treatment modalities just aim to ease symptoms of the disorder and delay the disease progression.
- Parkinson’s disease medications- PSP has similar kinds of symptoms to Parkinson’s, so medications used in Parkinson’s have been tried in PSP patients. Botox injection around your eye muscles can improve eyelid spasms.
- Bifocal eyeglasses may help in looking downward
- Speech and swallowing evaluations, to help you learn safer swallowing techniques.
- Physical therapy and occupational therapy may help to improve in making balance while walking.
Medications
Currently, there are no medications for progressive supranuclear palsy but drugs like levodopa, amantadine, and other drugs that are used for treating Parkinson’s disease are used. These drugs have been found to be little effect in people with early-stage PSP. The effect of these drugs can last for a few years and has been found to reduce stiffness and improve balance in patients.
Individuals with PSP often suffer from depression, in such cases, antidepressants are prescribed. These may also help individuals with sleeping problems, pain and stiffness, and balance.
Stem Cell Therapy for Progressive Supranuclear Palsy (PSP)
Stem cell Therapy is coming up as a powerful new therapeutic strategy for a wide spectrum of neurological disorders such as Parkinson’s disease, Alzheimer’s disease, multiple sclerosis, muscular dystrophy, etc. Stem cells are basic building blocks of the body that have unique characteristics of self-renewal and differentiation to different kinds of cells. Medical scientists are exploring the potential ability of stem cells to regenerate lost or damaged tissues to treat many diseases that are non-treatable with traditional therapies.
Stem cells can be extracted from the bone marrow and adipose tissue that provide an abundant supply of stem cells and thus are considered to be the most potent choice of stem cell suppliers. Bone marrow or adipose-derived stem cells differentiated into glial-like cells release a range of neurotrophic factors, which provides neuro-protection and neural-regenerative effects that further support the repairing of damaged nerves.
Recently a published case study of a 71-year-old patient with progressive supranuclear palsy showed no significant adverse events and delayed the progression of neurological deficits by achieving functional improvement in the follow-up period after having autologous adipose tissue-derived mesenchymal stem cells injection. Still, a lot needs to be explored to utilize the full potential of stem cell therapy. It is expected that continued research will pave the way for new treatment modalities devastating medical conditions like progressive supranuclear palsy. With these miracles of modern medicine, it will become possible to live a happier life over a longer period of time.
Alternative Treatments for PSP
There are several other lifestyle choices one can make to cope up with progressive supranuclear palsy. Individuals with PSP should stay mentally, physically, and socially active as long as they are in a position to do so.
- Regular exercise keeps your physical health flexible and strong and vitalizes your mind. A physiotherapist can suggest safe exercises to deal with PSP. The use of walking aids can reduce the danger of falling and help the person.
- A balanced diet including low-fat proteins and plenty of fruits and vegetables should be consumed by patients. This helps in the prevention of malnutrition and constipation and maintains a healthy weight.
- Individuals should engage themselves in mental activities. Interactive activities like playing games, reading, puzzles, etc are advised to people with PSP. The activities are of optimum difficulty level in order to avoid frustration in the patients.
- Socializing with other people can prove to be effective for PSP patients. It stimulates the brain and is enjoyable for such individuals. A lot of senior centers and community centers have special activities which are appropriate for people with progressive supranuclear palsy.
- It should be noted that such individuals should avoid smoking as it could be dangerous in terms of health and safety.
For free consultation on Stem Cell Therapy for Progressive Supranuclear Palsy (PSP), Connect with Advancells at [email protected], and you can also give us a call on +91-9654321400 for Your Inquiries.
Hi My mum has progressive supernuclear palsy and is currently aged 63. her symptoms started at age 58 (falls). She is at the stage now where she cannot stand at all, her jaw is locked and she suffers with repeat chest infections because of fluid getting into her lungs. I have looked at stem cell treatments and wondered if someone in her stage would be a candidate for stem cell replacements? What does the procedure entail and are you based in the UK?
Dear kaye
Thank you for trusting Advancells. As specified you mom is suffering with supranuclear palsy, which is a neurodegenerative disorders and is progressive. Stem cells can be helpful to delay progression by being differentiated into cells of neuronal origin. However, her repeated chest infection can be a point of concern for us. It will be better if you send her exact details of her current medical condition, which will be assessed by expert medical professionals on our panel to assess exact cause of her chest infection. These reports can be mailed to us @ [email protected] or even whatsapp @ +91-9654321400. We are based in India and are happy to help you
Thanks & Regards
Hi, my mom is suffering from PSP from last 3-4 yrs. She is 67 yrs old. She can’t walk and talk. Now she is not able to swallow anything except liquid item and that is also very difficult. Is their any possibility to cure her.
Dear Bindu,
We request to you please update us your Mom latest medical Report. we will get back to you with the full treatment protocol. For any further queries you are request to get in touch with us on [email protected] or WhatsApp/Call Us: at +91-9654321400.
Thanks & Regards,
Advancells.com
Hi my mother has psp. She is bedridden. She cannot walk or move and is incredibly stiff. She cannot talk however I do believe she recognises me as she sometimes smiles at me. I would like to be able to improve her life and at least be able to communicate. It’s as if she’s trapped in her own body. Please help.
Dear Liana,
Thank you for contacting Advancells. Stem cells are the naive foundation of the body with an ability to potentially differentiate into all cell types including neuronal origin. Progressive Supranuclear Palsy is a neurodegenerative disorder that is progressive in nature, and hence previous studies have indicated that the treatment should be offered immediately. Before committing anything to you, our clinical experts like to review your recent medical reports to understand her current medical condition. Please send us the same to [email protected] or call at +91 9654321400
Hi my mom has psp and cbd she is bed ridden. I want to be able to give her a chance to still have some type of life before she passes. How can I go about getting the stem cell therapy for her and what are the costs.
Thomas bell
Dear Thomas bell,
Thank you for contacting Advancells.
We would request you to share recent relevant medical reports and clinical history of the patient for us to revert with an opinion. Please feel free to contact in case of any query Whatsapp number at +91-9654321400.
Thanks & Regards
Advancells Support Team
PSP patient
Same thing with my father, do you know if today’s medics can help me ,I would pay any money i would do anything, do you know any idea?
Hi, My sister has been diagnosed with PSP last year and within a year, she can’t walk, has difficulty swallowing and there is an infection sign on her back. She lives in Sweden and I live in the U.S. and will be visiting her next week.
Is there anyway to save her or minimize the symptoms?
Thank you for your time!
Dear Mehrnoosh,
Can you please share detailed medical reports of your Sister to us at [email protected] or whatsapp them to +91-9654321400; so that we would assess your case through expert medical professionals on our panel and get back to you at the earliest.
Thanks & Regards
Advancells support Team.
S krishna reddy
I am doctor orthopaedics said to suffering from psp by Neurophysycian I am aged about59 years I had no complication except slurred speech altered gait since 1year Neurophysycian has said atypical Parkinsonism
after using Levodopa @parktedine he said no treatment for that is there any treatment is it correct dignosis
Dear Dr. Reddy,
Thank you for contacting Advancells. Sir as per your query, you have been suffering with progressive supranuclear palsy, as confirmed by your neurophysician; however, you have later mentioned about atypical parkinsonism, which is a bit confusing. Although, slurred speech and altered gait are typical symptoms of PSP i.e. supranuclear palsy, we need to go through your recent reports or medical analysis so as to understand your exact case. Please mail all your latest reports to [email protected] or whatsapp them to +919654321400.
As soon as, we receive your reports, we will get them analyzed by expert neurophysicians on our panel and will get back to you with a definitive treatment plan.
Thanks & Regards
I was diagnosed with psp 2 years ago by doctor marissa Dean at the university of Alabama Birmingham. My symptoms are slurred speech and I fall a lot. Can you help me.
Dear Mr. Kenneth
Thank you for contacting Advancells, please send your recent medical reports; so that we will be able to help you out with the detailed analysis of your condition. Stem cells can offer help for your condition, depending upon the body’s ability and other medical parameters. Kindly mail your reports to [email protected]; you can also whatsapp details on +91-9654321400.
Can I have more information about stem cell therapy for PSP and the cost of treatment.
Dear Kitty,
Thank you for contacting Advancells. You can get send your queries at [email protected] or WhatsApp us at +91-9654321400 and our team will get in touch with you.
I like
Hello My mom is 64 yrs old and sufferring from psp past 3 years.
She keeps falling and injures herself.she walks slowly.she eats but sometimes has problem with food going in the wind pipe.her memory is very sharp except sometimes she goes offtrack.her eye movement is not very okay.Please advise if some treatment can help.
Dear Tracy Dsouza,
Can you please share detailed medical reports of your mom to us at [email protected] or whatsapp them to +91-9654321400; so that we would assess your case through expert medical professionals on our panel and get back to you at the earliest.
Thanks & Regards
Advancells support Team.
Psp diesease
Hello Kanuj midha,
Progressive supranuclear palsy (PSP) is one of the diseases that typically affects elder people around the age of 60, and is rarely occur in people under the age of 40. PSP is a progressive brain disorder characterized by gait and balance difficulties and loss of eye coordination movements. As disorder name indicates that disease gets worsen (progressive) with time and can lead to life-threatening complication such as pneumonia and swallowing problems. PSP disorder is caused by deterioration of cells in certain part of the brain above nerve cell cluster called nuclei (supranuclear) that control movement, vision and thinking.
For any further queries you are request to get in touch with us on [email protected] or WhatsApp/Call Us: at +91-9654321400.
Thanks & Regards
Advancells Support Team
My wife aged 63 diagnosed PSP in 2020 in Lucknow sgpgi. After that I approached to indraprasth Apolo delhi They are saying that there is no cure of PSP in allopathy. I also approached Yogpeeth haridwar but that is also not effective treatment. To start stem cell therapy what medical reports required. Wether previous reports and present symptoms are anough or not.
Dear Ram Mangal Singh, We are sorry to hear about your wife’s condition. Stem cells can offer help for her condition, depending upon the body’s ability and other medical parameters. We request you to please send us your wife’s medical reports at [email protected] or WhatsApp us at +91-965421400. Our team will get in touch with you after reviewing the report. Thank you.
My father who is 65 has been living with PSP from last 7 years, It all stared with writing crunch and now he has tendency to fall backward, he is unable to walk properly, he has problem in swallowing food, he is loosing his voice.
he does Yoga and Physiotherapy daily and body massage once in week.
I have shared his reports to u on whatsapp
Thank you so much mohit. We have received your query, however you have sent only a prescription letter with list of medicines. Although, we need to review your case with latest MRI findings (Brain and Spine) with EMG analysis as well as symptoms based clinical history of the patient.
Once we receive these investigations, we would be able to review your case with our paneled specialist. Please send them to 9654321400 or mail them to [email protected]
Thanks & Regards
Hi ,
My father is 65 year old and 2year back ,he diagnosed to have psp,
He already has rheumatoid arthritis and htn, 1year before diagnosis he was misdiagnosed with Parkinson’s and treated for that,but medicine showed adverse effect on him and we stopped the treatment, but since one year he taking proper medicine for psp,but disease is progressive enough so that he developed many complication like recently admitted for pleural effusion.
We are very keen to know about stemcell treatment.is it curable by this?
Dear Nishi
Thank you for contacting Advancells. Although psp is a type of neurodegenerative disorder that is not progressive in nature; it should always be preferred to avail right treatment on time. Stem cells are the cells with the potential to differentiate into cells of neuronal origin, so whatever degeneration of neurons has happened so far the same can be recovered with generation of new neurons. The extent of regeneration is quite individualistic and depends upon the body’s ability to react. I would further request you to send his recent medical reports to us at [email protected] or WhatsApp them at +919654321400. This will further help us to assess his present medical condition and get back to you with appropriate protocols.
Hi, My father now aged 64 is suffering from all of the worsening symptoms that were mentioned in this article. He was diagnosed with PSP
3 years ago and no medicine or treatment seems to be arresting the progress of this disease. Would like to know if there is any possibility of getting him cured. Has anyone with PSP ever been able to get any better from this treatment?
Dear Tejes,
We request to you please update us your latest medical Report. we will get back to you with the full treatment protocol & Cost. For any further queries, you are requesting to get in touch with us on [email protected] or WhatsApp/Call Us: at +91-9654321400.
Thanks & Regards
Advancells Support Team
Father is 67 years old.
Diagnosed with PSP about 4 years ago.
We just finished a Clinical at the Medical University of South Carolina.
Very interested in your findings. Can you help?
Thanks
Dear Dennis,
We request to you please update us your Father latest medical Report. we will get back to you with the full treatment protocol & Cost. For any further queries you are request to get in touch with us on [email protected] or WhatsApp/Call Us: at +91-9654321400.
Thanks & Regards
Advancells Support Team
MY husband is 3 years with PSP. He can walk with some holding him. what to know more about sterm cells
Dear Eleanor
Thank you for contacting Advancells. PSP is a type of neurodegenerative disorder, which is progressive in nature and is associated with slow neuronal degeneration. Stem cells have been proven to differentiate into cells of neuronal origin and thus can stop the progression, facilitate the production of new neurons and further allow the decrease in wastage. However, it should also be noted that results are very patient-specific; and hence we need the latest medical reports of your husband for expert analysis; on the basis of which, we can offer the best treatment plan. Kindly drop in the same to our whatsapp number +91-9654321400; or mail us at [email protected].
thanks & regards
Do you know of any clinical trial for PSP in Singapore? My brother-in-law, a heart surgeon in his early 70s has just been diagnosed with the condition. Thanks.
Dear W Mills,
There are no recent reports of clinical trials for PSP but in case you are looking for some alternative effective therapies, you can consult at [email protected] .
Regards,
www.advancells.com
Hello my grandad was diagnosed with PSP around a year ago. He’s 80 years old and already had numerous health problems before being diagnosed such as Hypoglycaemia, Plural Plax, Fibulation, COPD, Heart Failure, Crushed Vertebrae’s, asma, Leaking heart valve and high blood pressure. His symptoms seem to be coming in different waves at different times, he currently is very constipated (it’s been around a week), his speech is somewhat fine but he is beginning to struggle; sometimes it’s like he’s speaking out loud with a conversation he’s had to himself in his head, struggling to hold cutlery but can eat somewhat okay, dazed out, can’t walk, legs have started to tense up to the point of no movement. National Health have been great we have all the equipment we need but I was just wondering if there’s someone I could speak to about what youse can do for us or answer some of my questions. Thank you.
Hello Abbi
Thank you for contacting Advancells. Although, looking at his age and other medical complications; we would suggest there are very fewer chances for stem cells to work; however, we would like to analyze his recent medical reports once if at all they are present. It would be a great help if you can send the same to [email protected] or may be Whatsapp us at +919654321400. Also, we are happy to extend any kind of support to you on-demand, and you can ask whatever questions you have, and we will readily answer you.
Hi my father has been diagnosed with PSP 11 months ago following some memory problems and some falls he is 64 years young.
He has high blood pressure and ANKA positive Vasculitis.
We don’t have his medical records currently.
Please could you send me more information on the stem treatment? And would this have to be carried out in India? We are in the UK.
Also if you could give me an idea of approximate costs please? For us to have an idea whether it would be worth obtaining his medical records. Many thanks.