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When you have peripheral arterial disease(PAD), your arteries get narrower and are unable to transport as much blood to your arms and legs. The peripheral vascular disease manifests in this way. One of the warning indications of PAD is cramps that begin while you’re moving and go away after a period of relaxation. It commonly manifests in your legs, but it can also develop in other areas of your body.

You may experience a heart attack or stroke more frequently if you don’t receive treatment. Additionally, it can force you to have to amputate a limb.

Causes of PAD

An obstruction in the arteries, the blood vessels that transport blood away from the heart, is the most frequent cause of PAD. Atherosclerosis is the name of this condition. It occurs when substances in your bloodstream, such as cholesterol and fat, combine to create plaques in your arteries.

Symptoms of PAD

Due to decreased blood flow to your legs, you may have muscle soreness or cramping. Claudication is the name for this kind of discomfort; when you walk or climb stairs, you typically feel it, but when you rest, it goes away. It may have an impact on several muscle groups, including feet, calf, thighs and hips.

If you have an advanced type of PAD, you might experience pain in your toes or feet even while you’re at rest. Other warning signs and symptoms could be:

  • The colour of your legs has changed.
  • Erectile dysfunction
  • a weakened leg
  • walking fatigue, especially in the legs
  • Having cooler legs than your arms
  • hair loss on your legs
  • Shiny leg skin

Diagnosis of PAD

Your doctor will begin by performing a physical examination to check for PAD symptoms. They might listen for a whooshing noise in the arteries in your legs and evaluate the blood flow in your feet and legs.

Other tests that you might undergo include:

  • Ultrasound
  • Angiogram
  • Blood tests
  • Ankle-branchial index

Treatment of PAD

A person with peripheral arterial disease (PAD), which is atherosclerosis, is at a higher risk of developing heart disease or stroke, both of which are atherosclerosis-related conditions. Because of this, PAD raises the chance of developing these more serious illnesses. To effectively treat PAD, risk factors for heart attack and stroke must be aggressively managed.

  • giving up smoking
  • managing blood pressure and diabetes
  • reducing triglycerides and low-density lipoprotein (LDL) cholesterol
  • using blood clot prevention medication
  • incorporating exercise under medical supervision into your daily life
  • Angioplasty
  • Surgery

In some advanced or untreatable cases, however, it is beyond our scope to prevent the progression of disease. Stem cell therapy is a promising approach in treatment of CLI. Stem cells aid in restoring blood supply which is lost in ischemic patients and prevent the need for amputation.